Two common assumptions made in most positron emission tomography (PET) cerebral
blood flow techniques have been examined in detail. These are (1) that the blood-borne …

An in vivo autoradiographic strategy is described for the measurement of local cerebral
blood flow in humans by positron emission tomography, based on an application of the …

A system for CBF measurement using an H215O autoradiographic method and positron
emission tomography (PET) has been designed and installed as a clinical tool. Following an …

A simplified mathematical model is described for the measurement of regional cerebral
blood flow by positron emission tomography in man, based on a modification of the …

This report describes a strategy for measurement of regional CBF that rigorously accounts
for differing tracer partition coefficients and recirculation, and is convenient for use with …

Factors are examined in this report which govern the uniqueness and sensitivity of regional
cerebral blood flow (rCBF), as determined by an in vivo autoradiographic strategy and …

The intravenous administration of H215O makes possible the quantitative evaluation of
regional changes in cerebral blood flow (CBF) during various neuronal activations in man …

Local CBF (LCBF) can be quantitated from positron computed tomographic (PCT) data and
physiologically based mathematical models by several general methods. Those using a …

A three-dimensional brain phantom has been developed to simulate the activity distributions
found in the human brain in the cerebral blood flow and metabolism studies employed in …

To evaluate the appropriate model for calculating regional cerebral blood flow (rCBF) with
PET and H215O, the values obtained from 1-and 2-compartment analyses were compared …