Emerging importance of molecular pathogenesis of vascular malformations in clinical practice and classifications

C Pang, CS Lim, J Brookes, J Tsui… - Vascular …, 2020 - journals.sagepub.com
Vascular malformations occur during early vascular development resulting in abnormally
formed vessels that can manifest as arterial, venous, capillary or lymphatic lesions, or in …

Genetics of vascular malformation and therapeutic implications

M Zuniga-Castillo, CL Teng… - Current Opinion in …, 2019 - journals.lww.com
Genetics of vascular malformation and therapeutic implicatio... : Current Opinion in Pediatrics
Genetics of vascular malformation and therapeutic implications : Current Opinion in Pediatrics …

How we approach genetics in the diagnosis and management of vascular anomalies

BA Setty, K Wusik, AM Hammill - Pediatric Blood & Cancer, 2022 - Wiley Online Library
Vascular anomalies are a heterogeneous group of disorders that are currently classified
based on their clinical and histological characteristics. Over the past decade, there have …

[HTML][HTML] A primer on a comprehensive genetic approach to vascular anomalies

AJ Borst, TA Nakano, F Blei, DM Adams… - Frontiers in pediatrics, 2020 - frontiersin.org
The field of vascular anomalies has grown tremendously in the last few decades with the
identification of key molecular pathways and genetic mutations that drive the formation and …

ISSVA classification of vascular anomalies and molecular biology

K Kunimoto, Y Yamamoto, M Jinnin - International Journal of Molecular …, 2022 - mdpi.com
Vascular anomalies include various diseases, which are classified into two types according
to the International Society for the Study of Vascular Anomalies (ISSVA) classification …

[HTML][HTML] Molecular changes associated with vascular malformations

A Fereydooni, A Dardik, N Nassiri - Journal of Vascular Surgery, 2019 - Elsevier
Vascular anomalies are typically classified into two major categories, vascular tumors and
vascular malformations. Most vascular malformations are caused sporadically by somatic …

Molecular basis of vascular anomalies

M Vikkula, LM Boon, JB Mulliken, BR Olsen - Trends in cardiovascular …, 1998 - Elsevier
Vascular anomalies comprise a heterogeneous group of disorders that are divided into
tumors (hemangiomas) and malformations. Recent advances in biomedical research …

Genetic basis and therapies for vascular anomalies

A Queisser, E Seront, LM Boon, M Vikkula - Circulation research, 2021 - Am Heart Assoc
Vascular and lymphatic malformations represent a challenge for clinicians. The identification
of inherited and somatic mutations in important signaling pathways, including the PI3K …

Vascular anomalies: molecular bases, genetic testing and therapeutic approaches.

S Paolacci, A Zulian, A Bruson, E Manara… - … angiology: a journal …, 2019 - europepmc.org
INTRODUCTION: Vascular anomalies encompass an extremely heterogeneous group of
congenital abnormalities of the vascular system. They include vascular tumors and …

Vascular anomalies caused by abnormal signaling within endothelial cells: targets for novel therapies

HL Nguyen, LM Boon, M Vikkula - Seminars in interventional …, 2017 - thieme-connect.com
Vascular anomalies arise as a consequence of improper development and maintenance of
the vasculature. Our knowledge on the pathophysiological bases of vascular anomalies has …