Epigenetics is the study of heritable changes in DNA or its associated proteins except
mutations in gene sequence. Epigenetic regulation plays fundamental roles in the …

Epigenetics examines heritable changes in DNA and its associated proteins except
mutations in gene sequence. Epigenetic regulation plays fundamental roles in kidney cell …

Chronic kidney disease (CKD) is a major public health concern and its prevalence and
incidence are rising quickly. It is a non-communicable disease primarily caused by diabetes …

The kidney is among the best characterized developing tissues, with the genes and
signaling pathways that regulate embryonic and adult kidney patterning and development …

Recent studies have demonstrated the association of altered epigenomes with lifestyle-
related diseases. Epigenetic regulation promotes biological plasticity in response to …

DNA methylation and histone modifications determine renal programming and the
development and progression of renal disease. The identification of the way in which the …

Kidney disease has complex and multifactorial pathophysiology and pathogenesis. Recent
studies have revealed that epigenetic methylation changes, namely DNA methylation …

Epigenomics has expanded our knowledge of gene architecture and regulation. Novel tools
and techniques have led to the emergence of 'multiomics' in which epigenomic profiling …

Epigenetics refers to a heritable change in the pattern of gene expression that is mediated
by a mechanism specifically not due to alterations in the primary nucleotide sequence. Well …

Epigenetic modifications are able to alter gene expression and include DNA methylation,
different histone variants, and post-transcriptional modifications (PTMs), such as acetylation …