Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer

S Yu, C Liu, Y Hou, J Li, Z Guo, X Chen, L Zhang… - Oncogene, 2022 - nature.com
Discrimination of malignancy from thyroid nodules poses challenges in clinical practice. We
aimed to identify the plasma metabolomic biomarkers in discriminating papillary thyroid …

Serum‐plasma matched metabolomics for comprehensive characterization of benign thyroid nodule and papillary thyroid carcinoma

FQ Huang, J Li, L Jiang, FX Wang… - … journal of cancer, 2019 - Wiley Online Library
Metabolomics offers a noninvasive methodology to identify metabolic markers for
pathogenesis and diagnosis of diseases. This work aimed to characterize circulating …

Metabolite analysis-aided diagnosis of papillary thyroid cancer

J Chen, Q Hu, H Hou, S Wang, Y Zhang… - Endocrine-Related …, 2019 - erc.bioscientifica.com
Thyroid cancer is the most frequent endocrine tumor with a growing incidence worldwide.
However, common diagnostic strategy for thyroid cancer classification is hardly to make a …

Integrated proteomic and metabolomic analysis of plasma reveals regulatory pathways and key elements in thyroid cancer

Z Sun, D Feng, L Jiang, J Tian, J Wang, W Zhu - Molecular Omics, 2023 - pubs.rsc.org
Thyroid cancer (TC) is the most common endocrine malignancy with increasing incidence in
recent years. Fine-needle aspiration biopsy (FNAB), as a gold standard for the initial …

[HTML][HTML] Plasma metabolic profiling of human thyroid nodules by gas chromatography-mass spectrometry (GC-MS)-based untargeted metabolomics

R Abooshahab, K Hooshmand, SA Razavi… - Frontiers in Cell and …, 2020 - frontiersin.org
One of the challenges in the area of diagnostics of human thyroid cancer is a preoperative
diagnosis of thyroid nodules with indeterminate cytology. Herein, we report an untargeted …

Metabolomics of papillary thyroid carcinoma tissues: potential biomarkers for diagnosis and promising targets for therapy

X Shang, X Zhong, X Tian - Tumor Biology, 2016 - Springer
Papillary thyroid carcinoma (PTC) is the most common pathological type of thyroid cancer.
Our study was to construct a tissue-targeted metabolomics analysis method based on …

Advances in metabolomics of thyroid cancer diagnosis and metabolic regulation

R Abooshahab, M Gholami, M Sanoie, F Azizi… - Endocrine, 2019 - Springer
Thyroid cancers (TCs) are the most frequent endocrine malignancy with an unpredictable
fast-growing incidence, especially in females all over the world. Fine-needle aspiration …

[HTML][HTML] Application of metabolomics in thyroid cancer research

A Wojakowska, M Chekan, P Widlak… - International journal of …, 2015 - hindawi.com
Thyroid cancer is the most common endocrine malignancy with four major types
distinguished on the basis of histopathological features: papillary, follicular, medullary, and …

Molecular pathological diagnosis of thyroid tumors using spatially resolved metabolomics

L Huang, X Mao, C Sun, T Li, X Song, J Li, S Gao… - Molecules, 2022 - mdpi.com
The pathological diagnosis of benign and malignant follicular thyroid tumors remains a
major challenge using the current histopathological technique. To improve diagnosis …

Metabolite signature of human malignant thyroid tissue: A systematic review and meta‐analysis

SA Razavi, B Khorsand, P Salehipour… - Cancer …, 2024 - Wiley Online Library
Background Thyroid cancer (TC) is the predominant malignancy within the endocrine
system. However, the standard method for TC diagnosis lacks the capability to identify the …