[HTML][HTML] Emerging roles for NLRC5 in immune diseases

J Wang, Y Liu, Q Xia, R Chen, J Liang… - Frontiers in …, 2019 - frontiersin.org
Innate immunity activates the corresponding immune response relying on multiple pattern
recognition receptors (PRRs) that includes pattern recognition receptors (PRRs), like NOD …

Expression regulation and function of NLRC5

Y Yao, Y Qian - Protein & cell, 2013 - academic.oup.com
The NOD like receptors (NLRs), a class of intracellular receptors that respond to pathogen
attack or cellular stress, have gained increasing attention. NLRC5, the largest member of the …

[HTML][HTML] Negative regulator NLRC3: Its potential role and regulatory mechanism in immune response and immune-related diseases

D Sun, J Xu, W Zhang, C Song, C Gao, Y He… - Frontiers in …, 2022 - frontiersin.org
NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating …

Overview of the anti-inflammatory function of the innate immune sensor NLRC3

Y Zhao, R Li - Molecular Immunology, 2023 - Elsevier
The innate immune system is the first line of defense for the host against any microbial
attack. It can quickly identify microorganisms and produce an immune response, removing …

NLRC5 limits the activation of inflammatory pathways

S Benko, JG Magalhaes, DJ Philpott… - The Journal of …, 2010 - journals.aai.org
Nod-like receptors (NLRs) are intracellular sentinel proteins that are implicated in the
detection of microbes and danger signals, thereby controlling several key innate immune …

Regulation of immune pathways by the NOD-like receptor NLRC5

M Lamkanfi, TD Kanneganti - Immunobiology, 2012 - Elsevier
Members of the nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR)
family are quickly emerging as critical regulators of innate and adaptive immune responses …

[HTML][HTML] NLRC5 functions beyond MHC I regulation—what do we know so far?

S Benkő, EG Kovács, F Hezel, TA Kufer - Frontiers in immunology, 2017 - frontiersin.org
NLRC5 is a member of the NLR family that acts as a transcriptional activator of MHC class I
genes. In line with the function of several related NLR proteins in innate immune responses …

NLRP9 in innate immunity and inflammation

B Mullins, J Chen - Immunology, 2021 - Wiley Online Library
The nucleotide‐binding domain leucine‐rich repeat containing receptors (NLRs) are a
family of evolutionarily conserved proteins. Several members of NLRs, notably NLRP1 …

[HTML][HTML] NLRP12 in autoimmune diseases

P Gurung, TD Kanneganti - Oncotarget, 2015 - ncbi.nlm.nih.gov
Nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are a group of
cytoplasmic sensors that survey danger signals released by invading pathogen or damaged …

Emerging major histocompatibility complex class I-related functions of NLRC5

ST Chelbi, AT Dang, G Guarda - Advances in immunology, 2017 - Elsevier
Recent evidence demonstrates a key role for the nucleotide-binding oligomerization domain-
like receptor (NLR) family member NLRC5 (NLR family, CARD domain containing protein 5) …