Radical polymerization inside living cells

J Geng, W Li, Y Zhang, N Thottappillil… - Nature …, 2019 - nature.com
Polymerization reactions conducted inside cells must be compatible with the complex
intracellular environment, which contains numerous molecules and functional groups that …

Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization

J Niu, DJ Lunn, A Pusuluri, JI Yoo, MA O'Malley… - Nature Chemistry, 2017 - nature.com
The capability to graft synthetic polymers onto the surfaces of live cells offers the potential to
manipulate and control their phenotype and underlying cellular processes. Conventional …

Polymer chemistry in living cells

Z Zhou, K Maxeiner, DYW Ng… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus The polymerization of biomolecules is a central operation in biology that
connects molecular signals with proliferative and information-rich events in cells. As …

Polymerization in living organisms

D Wu, J Lei, Z Zhang, F Huang, M Buljan… - Chemical Society …, 2023 - pubs.rsc.org
Vital biomacromolecules, such as RNA, DNA, polysaccharides and proteins, are
synthesized inside cells via the polymerization of small biomolecules to support and multiply …

End-functionalized polymers by controlled/living radical polymerizations: synthesis and applications

D Zhou, LW Zhu, BH Wu, ZK Xu, LS Wan - Polymer Chemistry, 2022 - pubs.rsc.org
The precise design of polymers with well-defined end functionality has received great
interest for synthesizing polymeric materials with advanced or distinctive properties. In the …

Controlled radical polymerization as an enabling approach for the next generation of protein–polymer conjugates

EM Pelegri-O'Day, HD Maynard - Accounts of Chemical Research, 2016 - ACS Publications
Conspectus Protein–polymer conjugates are unique constructs that combine the chemical
properties of a synthetic polymer chain with the biological properties of a biomacromolecule …

From precision polymers to complex materials and systems

JF Lutz, JM Lehn, EW Meijer… - Nature Reviews Materials, 2016 - nature.com
Complex chemical systems, such as living biological matter, are highly organized structures
based on discrete molecules in constant dynamic interactions. These natural materials can …

[HTML][HTML] Site-selected in situ polymerization for living cell surface engineering

Y Zhong, L Xu, C Yang, L Xu, G Wang, Y Guo… - Nature …, 2023 - nature.com
The construction of polymer-based mimicry on cell surface to manipulate cell behaviors and
functions offers promising prospects in the field of biotechnology and cell therapy. However …

[HTML][HTML] Artificial cell synthesis using biocatalytic polymerization-induced self-assembly

A Belluati, S Jimaja, RJ Chadwick, C Glynn… - Nature Chemistry, 2024 - nature.com
Artificial cells are biomimetic microstructures that mimic functions of natural cells, can be
applied as building blocks for molecular systems engineering, and host synthetic biology …

Living radical polymerization as a tool for the synthesis of polymer‐protein/peptide bioconjugates

J Nicolas, G Mantovani… - Macromolecular rapid …, 2007 - Wiley Online Library
Combinations of synthetic and natural macromolecules offer a route to new functional
materials. While biological and polymer chemistry may not be natural bedfellows, many …