The prevalence of thyroid carcinoma is increasing and represents the most common
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …

Although papillary thyroid cancer (PTC) is curable with excellent survival rate, patients with
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …

Background Papillary thyroid cancer has been associated with chronic inflammation. A
systematic understanding of immune cell infiltration in PTC is essential for subsequent …

Background Papillary thyroid carcinoma (PTC) is the main pathological type of thyroid
carcinoma (TC). Gender is a prominent background parameter for patients with PTC. Here …

Background Papillary thyroid carcinoma (PTC) follows an indolent course; however, up to
30% of patients develop recurrent disease requiring further treatment. Profiling PTC immune …

Immune system plays a key role in cancer prevention as well as in its initiation and
progression. During multistep development of tumors, cells must acquire the capability to …

Objectives The understanding of the mechanisms underlying thyroid cancer immune escape
can lead to the identification of new molecular targets and/or efficacy biomarkers. For this …

The tumor microenvironment heterogeneity of papillary thyroid cancer (PTC) is poorly
characterized. The relationship between PTC and Hashimoto thyroiditis (HT) is also in …

Thyroid cancer is an excellent model for studying tumor immune microenvironment, as it
often shows local signs of an immune response. The tumor immune microenvironment of …

Background The tumor microenvironment (TME) plays a pivotal role in cancer progression in
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …