[HTML][HTML] Altered DNA methylation in kidney disease: useful markers and therapeutic targets

K Hayashi - Clinical and experimental nephrology, 2022 - Springer
Recent studies have demonstrated the association of altered epigenomes with lifestyle-
related diseases. Epigenetic regulation promotes biological plasticity in response to …

[HTML][HTML] DNA methylation dysfunction in chronic kidney disease

D Ingrosso, AF Perna - Genes, 2020 - mdpi.com
Renal disease is the common denominator of a number of underlying disease conditions,
whose prevalence has been dramatically increasing over the last two decades. Two aspects …

The emerging role of epigenetic methylation in kidney disease

L Wen, H Yang, L Lin, L Ma, P Fu - Current Medicinal Chemistry, 2022 - ingentaconnect.com
Kidney disease has complex and multifactorial pathophysiology and pathogenesis. Recent
studies have revealed that epigenetic methylation changes, namely DNA methylation …

Targeting DNA Methylation in Podocytes to Overcome Chronic Kidney Disease

K Hayashi - The Keio Journal of Medicine, 2023 - jstage.jst.go.jp
The number of patients with chronic kidney disease (CKD) is on the rise worldwide, and
there is urgent need for the development of effective plans against the increasing incidence …

Targeting DNA methylation in diabetic kidney disease: A new perspective

V Akhouri, S Majumder, AB Gaikwad - Life Sciences, 2023 - Elsevier
Diabetic kidney disease (DKD) is a leading diabetic complication causing significant
mortality among people around the globe. People with poor glycemic control accompanied …

Epigenetics of kidney disease

N Wanner, W Bechtel-Walz - Cell and tissue research, 2017 - Springer
DNA methylation and histone modifications determine renal programming and the
development and progression of renal disease. The identification of the way in which the …

Epigenetics in kidney diseases

H Ding, L Zhang, Q Yang, X Zhang, X Li - Advances in clinical chemistry, 2021 - Elsevier
Epigenetics examines heritable changes in DNA and its associated proteins except
mutations in gene sequence. Epigenetic regulation plays fundamental roles in kidney cell …

Investigation of epigenetics in kidney cell biology

LX Li, E Agborbesong, L Zhang, X Li - Methods in cell biology, 2019 - Elsevier
Epigenetics is the study of heritable changes in DNA or its associated proteins except
mutations in gene sequence. Epigenetic regulation plays fundamental roles in the …

[HTML][HTML] Are alterations in DNA methylation related to CKD development?

J Rysz, B Franczyk, M Rysz-Górzyńska… - International Journal of …, 2022 - mdpi.com
The modifications in genomic DNA methylation are involved in the regulation of normal and
pathological cellular processes. The epigenetic regulation stimulates biological plasticity as …

[HTML][HTML] DNA methylation in peripheral blood is associated with renal aging and renal function decline: a national community study

PL Yang, TS Lai, YH Chou, LC Lai, SL Lin, YM Chen - Clinical Epigenetics, 2024 - Springer
Background Older patients are at risk for acute kidney injury and chronic kidney disease.
Age-related increases in DNA methylation at CpG islands have been linked to aging-related …