Simple Summary Angiogenesis belongs to the most clinical characteristics of colorectal
cancer (CRC) and is strongly linked to the activation of Wnt/β-catenin signaling. The most …

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …

The Wnt/β-catenin signaling pathway is a growth control pathway involved in various
biological processes as well as the development and progression of cancer. Colorectal …

Aberrant Wnt/β-catenin signaling has often been reported in different cancers, particularly
colorectal cancer (CRC), and this signaling cascade is central to carcinogenesis …

Colorectal cancer is the second most common cancer in females and the third most common
cancer diagnosed in males (Torre et al. 1). In 2012, there were about 1.4 million cases and …

Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

ABSTRACT β-catenin has two distinct functions, namely, maintaining cell-to-cell adhesion
and mediating the Wnt/β-catenin signal transduction pathway, which plays pivotal roles in …

The Wnt/β-catenin signaling pathway is highly conservative. β-catenin is the key molecule in
this pathway. The β-catenin target genes regulate cell proliferation and apoptosis. Since Wnt …

The Wnt/β-catenin signaling pathway has been implicated as the central mechanism that
drives colorectal carcinogenesis. Its activation is historically due to mutation on APC …

The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …