The safety profile of vedolizumab in ulcerative colitis and Crohn's disease: 4 years of global post-marketing data

RD Cohen, F Bhayat, A Blake… - Journal of Crohn's and …, 2020 - academic.oup.com
Abstract Background and Aims Vedolizumab is a gut-selective antibody to α 4 β 7 integrin,
approved to treat moderate-to-severe ulcerative colitis and Crohn's disease in adults …

Long‐term safety of vedolizumab for inflammatory bowel disease

EV Loftus Jr, BG Feagan, R Panaccione… - Alimentary …, 2020 - Wiley Online Library
Background Vedolizumab, a gut‐selective α4β7 integrin antibody, is approved for
moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD). Aim To report …

Real-world effectiveness and safety of vedolizumab for the treatment of inflammatory bowel disease: the Scottish vedolizumab cohort

N Plevris, CS Chuah, RM Allen, ID Arnott… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background & Aims Vedolizumab is an anti-a4b7 monoclonal antibody that is
licensed for the treatment of moderate to severe Crohn's disease and ulcerative colitis. The …

The safety of vedolizumab for ulcerative colitis and Crohn's disease

JF Colombel, BE Sands, P Rutgeerts, W Sandborn… - Gut, 2017 - gut.bmj.com
Objective Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of
ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the …

Long-term efficacy of vedolizumab for ulcerative colitis

EV Loftus Jr, JF Colombel, BG Feagan… - Journal of Crohn's …, 2017 - academic.oup.com
Abstract Background and Aims: The GEMINI long-term safety [LTS] study is a continuing
phase 3 trial investigating the safety and efficacy of vedolizumab, an α4β7 integrin …

Long-term efficacy of vedolizumab for Crohn's disease

S Vermeire, EV Loftus Jr, JF Colombel… - Journal of Crohn's …, 2017 - academic.oup.com
Abstract Background and Aims: Vedolizumab is a gut-selective α4β7 integrin antagonist
therapy for ulcerative colitis and Crohn's disease. The GEMINI long-term safety [LTS] trial is …

[HTML][HTML] Retrospective analysis of safety of vedolizumab in patients with inflammatory bowel diseases

J Meserve, S Aniwan, JL Koliani-Pace, P Shashi… - Clinical …, 2019 - Elsevier
Background & Aims There are few real-world data on the safety of vedolizumab for treatment
of Crohn's disease (CD) or ulcerative colitis (UC). We quantified rates and identified factors …

[HTML][HTML] Efficacy and safety of vedolizumab in ulcerative colitis and Crohn's disease patients stratified by age

V Yajnik, N Khan, M Dubinsky, J Axler, A James… - Advances in …, 2017 - Springer
Introduction The efficacy and safety of vedolizumab, a gut-selective α 4 β 7 integrin antibody,
were demonstrated in the GEMINI 1 and GEMINI 2 clinical trials of adults aged 18–80 years …

Long-term clinical experience with vedolizumab in patients with inflammatory bowel disease

A Parikh, I Fox, T Leach, J Xu, C Scholz… - Inflammatory Bowel …, 2013 - academic.oup.com
Background Vedolizumab, a gut-selective, anti-inflammatory monoclonal antibody, has
shown preliminary efficacy in ulcerative colitis (UC) and Crohn's disease (CD). We report …

Vedolizumab as the first line of biologic therapy for ulcerative colitis and Crohn's disease–a systematic review with meta-analysis

M Attauabi, GR Madsen, F Bendtsen… - Digestive and Liver …, 2022 - Elsevier
Background The efficacy and safety of vedolizumab in bio-naïve patients with ulcerative
colitis (UC) and Crohn's disease (CD) remain unknown. Aims To perform a meta-analysis …