Melanin-concentrating hormone (MCH) is a small cyclic peptide expressed in all mammals,
mainly in the hypothalamus. MCH acts as a robust integrator of several physiological …

Extensive studies in rodents with melanin-concentrating hormone (MCH) have
demonstrated that the neuropeptide hormone is a potent orexigen. Acutely, MCH causes an …

Melanin-concentrating hormone (MCH) is a cyclic neuropeptide, which centrally regulates
food intake and stress. MCH induces food intake in rodents and, more generally, acts as an …

Melanin-concentrating hormone (MCH) is a cyclic peptide that mediates its effects by the
activation of two G-protein-coupled seven transmembrane receptors (MCHR1 and MCHR2) …

Given the increased prevalence of obesity and its associated comorbidities, understanding
the mechanisms through which the brain regulates energy balance is of critical importance …

The hypothalamic neuropeptide melanin-concentrating hormone (MCH) has been
implicated in a variety of physiological functions including the regulation of feeding and …

In recent years, the key role of melanin-concentrating hormone (MCH) in regulating
mammalian energy balance has been confirmed through several lines of evidence. When …

Melanin-concentrating hormone (MCH) is a 19-amino-acid cyclic peptide which was
originally found to lighten skin color in fish that is highly conserved among many species …

Melanin-concentrating hormone (MCH) is a cyclic 19-amino-acid neuropeptide that has
been considered to play a key role in the regulation of feeding and energy homeostasis. To …

Over the past ten years, tremendous advances in our understanding of the role of the
hypothalamic neurohormone, melanin-concentrating hormone (MCH), and its involvement in …