Nuclear medicine in general and PET imaging in particular have long provided the
opportunity for quantitative measurements of human physiology in vivo. Practical …

We investigated the optimal scan time for obtaining the maximal signal-to-noise (S/N) ratio in
cerebral blood flow (CBF) measured by PET imaging following 15O-water bolus injection …

Recently Raichle and colleagues described an implementation of the PET/autoradiographic
technique for the measurement of regional cerebral blood flow with intravenously …

Abstract [15 O]-labeled water has been used to measure brain blood flow for many years
(Herscovitch, et al. 1983). While now considered a common procedure, it remains difficult to …

Regional cerebral blood flow (CBF) can be quantified using oxygen-15-labelled water ([15
O] H 2 O) and positron emission tomography. In this overview, first a description is given of …

Cerebral blood flow quantification is a vital diagnostic tool for disease monitoring and used
for diagnosing a variation of pathological conditions. The human brain requires roughly …

[en] Initial results on measuring local cerebral blood flows (LCBF) and the partition
coefficient (V) of water in brain tissues with positron computed tomography (PCT), using a …

The investigation of human cerebral function has been one of the most challenging subjects
in the last century. Imaging studies that use positron emission tomography (PET) with [O-15] …

Two common assumptions made in most positron emission tomography (PET) cerebral
blood flow techniques have been examined in detail. These are (1) that the blood-borne …

A system for CBF measurement using an H215O autoradiographic method and positron
emission tomography (PET) has been designed and installed as a clinical tool. Following an …