Objective: The purpose of this post hoc analysis was to evaluate the incidence and timing of
taper/posttherapy–emergent adverse events (TPAEs) following discontinuation of long-term …

Background: Second-generation antidepressants dominate the management of patients with
major depressive disorder (MDD). Evidence on the general and comparative benefits and …

Background: Major depressive disorder is characterized by the presence of at least five of
nine specific symptoms that contribute to clinically significant functional impairment. This …

Objective: The purpose of this study was to assess long-term safety and tolerability of
desvenlafaxine (administered as desvenlafaxine succinate) in children and adolescents with …

Objective: The goal of a non-inferiority study is to test whether a new treatment has at least
as much efficacy as an established treatment1. The purpose of this non-inferiority study was …

Background Approved doses of antidepressants in Japan are usually lower than those in the
USA and European Union, but to date meta-analyses comparing antidepressants have all …

Review: venlafaxine is more effective than selective serotoninreuptake inhibitors for
depression | BMJ Evidence-Based Medicine Skip to main content Viewing from: Google …

BACKGROUND: Serotonergic and adrenergic enhancement may be synergistic and more
effective than serotonergic enhancement alone in treating depression. The dual serotonin …

The aim of the present paper was to compare the efficacy and safety of duloxetine with
paroxetine in the acute treatment of major depressive disorder (MDD). In a randomized …

Background: The comparative efficacy of selective serotonin reuptake inhibitors (SSRIs) and
serotoninnorepinephrine reuptake inhibitors (SNRIs) was recently debated. Meta-analyses …