AUDA as a modulator of lipid profile and endothelial function in diet induced hypercholesterolemia in rats

K Ragab, L Bayoumi, SZ Nassar… - Bulletin of Egyptian …, 2019 - besps.journals.ekb.eg
Background: Epoxyeicosatrienoic acids (EETs) are cytochrome P450 metabolites of
arachidonic acid produced by the vascular endothelium and act as important regulators of …

Therapeutic effects of the soluble epoxide hydrolase (sEH) inhibitor AUDA on atherosclerotic diseases

J Zhang, YS Liu, QH Lu - Die Pharmazie-An International …, 2015 - ingentaconnect.com
In this study, we aimed to detect the effects of the soluble epoxide hydrolase (sEH) inhibitor
12 (3-adamantan-1-yl-ureido)-dodecanoic acid (AUDA) on atherosclerotic diseases and to …

Effect of EDTA on Biochemical Markers of Artherosclerosis in Palm Kernel Oil Diet-Induced Hyperlipidaemic Albino Rats

KS Adedapo - Archives of Basic and Applied Medicine, 2017 - ojshostng.com
Ethylene diaminetetraacetic acid (EDTA) is a synthetic amino acid used orally and
intravenously to cleanse, detoxify, and remove heavy metals from the body. Atherosclerosis …

Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation, and dyslipidemia

LN Zhang, J Vincelette, Y Cheng, U Mehra… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Epoxyeicosatrienoic acids (EETs) have been shown to have antiinflammatory
effects and therefore may play a role in preventing vascular inflammatory and atherosclerotic …

Vascular-protective Effects of High Density Lipoprotein Include the Down-regulation of the AT1 Receptor

F Spillmann, S Van Linthout, M Lorenz, M Meloni… - 2006 - Am Heart Assoc
Introduction: Angiotensin II exerts via stimulation of the AT1 receptor (AT1R) inflammatory
and apoptotic stimuli which are involved in the induction of endothelial dysfunction. Given …

High fat diet containing cholesterol induce aortic aneurysm through recruitment and proliferation of circulating agranulocytes in apoE knock out mice model

K Gopal, K Kumar, R Nandini, P Jahan… - Journal of thrombosis …, 2010 - Springer
We studied and compared the efficiency of induction aneurysm in apo E mice by using high
fat diet and Ang II. Aneurysm induced in 6 week old male apo E−/− mice by subcutaneous …

Altered aortic reactivity by diabetes mellitus in ovariectomized rats: role of epoxyeicosatrienoic acids (EETs)

A Čavka, I Grizelj, Z Mihaljević, A Ćosić, S Novak… - Physiology 2014, 2014 - croris.hr
Background: Epoxyeicosatrienoic acids (EETs), the cytochrome P450 epoxygenase
metabolites of arachidonic acid, are vasodilators believed to be the endothelium-derived …

Potential of Flavonoids on Aortic Histopathological Improvement of ApoE-/-Mice With High-Fat Diet: A Systematic Literature Review

H Adyatma, N Hardini, MS Thadeus - Buletin Farmatera, 2021 - jurnal.umsu.ac.id
Non-communicable diseases account for more than 36 million deaths every year (63% of all
deaths). Globally, non-communicable diseases (NCDs) that cause the most deaths each …

[PDF][PDF] Dehydroabietic Acid Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice and VCAM-1 Expressions in-vitro

X Liang, Y Wu - Sains Malaysiana, 2022 - ukm.my
Dehydroabietic acid (DHA) is an analog of abietic acid (AA) for cardiovascular disease
prevention, known to act pharmacologically against aging, inflammation, bacterial infections …

Aster glehni extract can ameliorate atherosclerosis through the regulation of adiponectin in ApoE knockout mice

HM Kim, YJ Lee, YN Jang, YM Han… - …, 2017 - atherosclerosis-journal.com
Aim: To study the effects of Aster glehni on atherosclerosis, several bio-markers related to
lipid metabolism and vascular diseases were estimated in the serum or aorta of …