Improved paclitaxel delivery with PEG-b-PLA/zein nanoparticles prepared via flash nanoprecipitation
W Ye, F Zhu, Y Cai, L Wang, G Zhang, G Zhao… - International Journal of …, 2022 - Elsevier
Polymeric micelle is a promising vehicle to improve the bioavailability and clinical outcomes
of paclitaxel (PTX) which has been proven effective in the treatment of a wide range of …
of paclitaxel (PTX) which has been proven effective in the treatment of a wide range of …
Dual-targeted controlled delivery based on folic acid modified pectin-based nanoparticles for combination therapy of liver cancer
Y Liu, Y Zong, Z Yang, M Luo, G Li… - ACS sustainable …, 2019 - ACS Publications
Dihydroartemisinin (DHA) as an effective anticancer drug is being concerned owing to the
excellent efficacy, but the poor solubility and premature release confine the clinical …
excellent efficacy, but the poor solubility and premature release confine the clinical …
Glucose-conjugated glutenin nanoparticles for selective targeting and delivery of camptothecin into breast cancer cells
Receptor-mediated drug delivery systems are a promising tool for targeting malignant cells
to suppress/inhibit the malignancy without disturbing healthy cells. Protein-based …
to suppress/inhibit the malignancy without disturbing healthy cells. Protein-based …
Targeted nanoparticles for the delivery of novel bioactive molecules to pancreatic cancer cells
V Sanna, S Nurra, N Pala, S Marceddu… - Journal of Medicinal …, 2016 - ACS Publications
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis
and limited therapeutic options. Therefore, there is an urgent need to identify new, safe, and …
and limited therapeutic options. Therefore, there is an urgent need to identify new, safe, and …
Self-assembled gemcitabine prodrug nanoparticles show enhanced efficacy against patient-derived pancreatic ductal adenocarcinoma
L Wu, F Zhang, X Chen, J Wan, Y Wang… - … applied materials & …, 2019 - ACS Publications
Effective new therapies for pancreatic ductal adenocarcinoma (PDAC) are desperately
needed as the prognosis of PDAC patients is dismal and treatment remains a major …
needed as the prognosis of PDAC patients is dismal and treatment remains a major …
Pectin-cysteine conjugate: synthesis and in-vitro evaluation of its potential for drug delivery
S Majzoob, F Atyabi, F Dorkoosh… - Journal of pharmacy …, 2006 - academic.oup.com
This study was aimed at improving certain properties of pectin by introduction of thiol
moieties on the polymer. Thiolated pectin was synthesized by covalent attachment of …
moieties on the polymer. Thiolated pectin was synthesized by covalent attachment of …
Engineering pectin-based hollow nanocapsules for delivery of anticancer drug
Multifunctional capsules have great applications in biomedical fields. In this study, novel
polysaccharide-based nanocapsules were prepared via a layer-by-layer technique using …
polysaccharide-based nanocapsules were prepared via a layer-by-layer technique using …
[HTML][HTML] Increased cytotoxic efficacy of protocatechuic acid in A549 human lung cancer delivered via hydrophobically modified-chitosan nanoparticles as an …
C Yee Kuen, T Galen, S Fakurazi, SS Othman… - Polymers, 2020 - mdpi.com
The growing incidence of global lung cancer cases against successful treatment modalities
has increased the demand for the development of innovative strategies to complement …
has increased the demand for the development of innovative strategies to complement …
Green synthesis of folic acid-conjugated gold nanoparticles with pectin as reducing/stabilizing agent for cancer theranostics
RM Devendiran, S kumar Chinnaiyan, NK Yadav… - RSC …, 2016 - pubs.rsc.org
In the present study pectin, a natural polysaccharide was employed for the one pot aqueous
synthesis of gold nanoparticles (GNPs). Pectin acted at the same time as both a reducing …
synthesis of gold nanoparticles (GNPs). Pectin acted at the same time as both a reducing …
Next-generation paclitaxel-nanoparticle formulation for pancreatic cancer treatment
Pancreatic cancer (PanCa) is a major cause of cancer-related death due to limited
therapeutic options. As pancreatic tumors are highly desmoplastic, they prevent appropriate …
therapeutic options. As pancreatic tumors are highly desmoplastic, they prevent appropriate …