Background: Naringenin, a member of the dihydroflavone family, has been shown to have a
protective function in multiple diseases. We previously demonstrated that naringenin played …

Background Cardiorenal syndrome is a complicated and bidirectional interrelationship
between the heart and kidneys. Naringenin (NG) is a naturally occurring flavonoid …

Background: Naringenin, a natural resource-derived flavanone, exhibits a plethora of
pharmacological properties. The present study aimed to investigate the effects of naringenin …

Genistein is a bioflavonoid mainly found in soybean. This study evaluated the effect of
genistein on vascular dysfunction and kidney damage in two-kidney, one-clipped (2K1C) …

Hypertension is a condition with chronic elevation of blood pressure and a common
preventable risk factor for cardiovascular disease with attendant global morbidity and …

Context: Naringenin, a flavonone and a nutritive antioxidant which is mostly obtained from
grapefruit, orange or tomato skin, has been extensively studied due to its radical scavenging …

Background Renin–angiotensin system triggers vascular remodeling and fibrosis during the
renovascular hypertensive two-kidney, one-clip (2K1C) model by oxidative-stress-mediated …

AIM To determine the effect of tempol in normal rats fed high salt on arterial pressure and the
balance between antagonist components of the renal renin-angiotensin system. METHODS …

Vascular remodeling due to hypertension is one of the major health challenges facing
countries around the world. Neohesperidin, a flavonoid glycoside found in citrus fruits, is an …

Objectives: We aimed to investigate the effects of berberine on renin–angiotensin system
(RAS) and pro-inflammatory cytokines, as well as its effects on blood pressure and renal …