[HTML][HTML] Sweroside ameliorates α-naphthylisothiocyanate-induced cholestatic liver injury in mice by regulating bile acids and suppressing pro-inflammatory responses

Q Yang, F Yang, J Gong, X Tang, G Wang… - Acta Pharmacologica …, 2016 - nature.com
Aim: Sweroside is an iridoid glycoside with diverse biological activities. In the present study
we investigated the effects of sweroside on α-naphthylisothiocyanate (ANIT)-induced …

[HTML][HTML] Resveratrol effectively attenuates α-naphthyl-isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms

T Wang, Z Zhou, L Sun, X Li, Z Xu, M Chen… - Acta Pharmacologica …, 2014 - nature.com
Aim: α-Naphthylisothiocyanate (ANIT) is a well-characterized cholestatic agent for rats. The
aim of this study was to examine whether resveratrol could attenuate ANIT-induced acute …

Different effects of ursodeoxycholic acid on intrahepatic cholestasis in acute and recovery stages induced by alpha-naphthylisothiocyanate in mice

L Zhang, H Su, Y Li, Y Fan, Q Wang, J Jiang… - Toxicology and Applied …, 2018 - Elsevier
The aim of this study was to determine the effect of ursodeoxycholic acid (UDCA) on the
alpha-naphthylisothiocyanate (ANIT)-induced acute and recovery stage of cholestasis …

Yinchenzhufu decoction protects against alpha-naphthylisothiocyanate-induced acute cholestatic liver injury in mice by ameliorating disordered bile acid homeostasis …

GF Wang, YY Li, R Shi, TM Wang, YF Li, WK Li… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Intrahepatic cholestasis is a common condition of many
liver diseases with few therapies. Yinchenzhufu decoction (YCZFD) is a representative …

Salvianolic acid B protects against ANIT-induced cholestatic liver injury through regulating bile acid transporters and enzymes, and NF-κB/IκB and MAPK pathways

S Li, R Wang, B Wu, Y Wang, F Song, Y Gu… - Naunyn-Schmiedeberg's …, 2019 - Springer
The purpose of this study was to investigate the pharmacological effects of salvianolic acid B
(SA-B) on α-naphthylisothiocyanate (ANIT)-induced cholestatic liver injury with the focus on …

[HTML][HTML] Oral administration of oleanolic acid, isolated from Swertia mussotii Franch, attenuates liver injury, inflammation, and cholestasis in bile duct-ligated rats

J Chai, X Du, S Chen, XC Feng, Y Cheng… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Background & aims: Oleanolic acid is abundantly distributed in Swertia mussotii Franch, a
Chinese traditional herb for the treatment of jaundice. However, the hepatoprotective role of …

Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct‐Ligated Rats

L Zhang, Y Cheng, X Du, S Chen… - Evidence‐Based …, 2015 - Wiley Online Library
Swertianlarin is an herbal agent abundantly distributed in Swertia mussotii Franch, a
Chinese traditional herb used for treatment of jaundice. To study the therapeutic effect of …

Swertiamarin, an active iridoid glycoside from Swertia pseudochinensis H. Hara, protects against alpha-naphthylisothiocyanate-induced cholestasis by activating the …

M Shi, J Tang, T Zhang, H Han - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Swertiamarin (SW), which belongs to iridoid glycosides, is
one of the main components of Swertia plants in Gentianaceae family, including Swertia …

[HTML][HTML] Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats

J Yan, G Xie, C Liang, Y Hu, A Zhao, F Huang, P Hu… - Scientific Reports, 2017 - nature.com
Cholestasis is a clinical disorder defined as an impairment of bile flow, and that leads to
toxic bile acid (BA) accumulation in hepatocytes. Here, we investigated the hepatoprotective …

[HTML][HTML] Sophocarpine protects mice from ConA-induced hepatitis via inhibition of the IFN-Gamma/STAT1 pathway

XX Sang, RL Wang, CE Zhang, SJ Liu… - Frontiers in …, 2017 - frontiersin.org
Sophocarpine is the major pharmacologically active compound of the traditional Chinese
herbal medicine Radix Sophorae Subprostratae which has been used in treating hepatitis …