[HTML][HTML] OmpA Protein-Deficient Acinetobacter baumannii Outer Membrane Vesicles Trigger Reduced Inflammatory Response

J Skerniškytė, E Karazijaitė, A Lučiūnaitė… - Pathogens, 2021 - mdpi.com
Multidrug resistant Acinetobacter baumannii shows a growing number of nosocomial
infections worldwide during the last decade. The outer membrane vesicles (OMVs) …

[HTML][HTML] Acinetobacter baumannii Outer Membrane Vesicles Elicit a Potent Innate Immune Response via Membrane Proteins

SH Jun, JH Lee, BR Kim, SI Kim, TI Park, JC Lee… - PloS one, 2013 - journals.plos.org
Acinetobacter baumannii is increasingly becoming a major nosocomial pathogen. This
opportunistic pathogen secretes outer membrane vesicles (OMVs) that interact with host …

[HTML][HTML] Differential proteomic analysis and pathogenic effects of outer membrane vesicles derived from Acinetobacter baumannii under normoxia and hypoxia

S Suzuki, P Subsomwong, K Narita, N Kawai, T Ishiai… - Plos one, 2023 - journals.plos.org
Acinetobacter baumannii is a major causative agent of nosocomial infections and its outer
membrane vesicles (AbOMVs) have been shown to be involved in pathogenicity by …

Outer membrane vesicles isolated from two clinical Acinetobacter baumannii strains exhibit different toxicity and proteome characteristics

ZT Li, RL Zhang, XG Bi, L Xu, M Fan, D Xie, Y Xian… - Microbial …, 2015 - Elsevier
Outer membrane vesicles (OMVs) are well-characterized virulence factors produced by
Gram-negative bacteria. Here, we isolated two clinical Acinetobacter baumannii strains, the …

In vitro study of virulence potential of Acinetobacter baumannii outer membrane vesicles

C Jha, S Ghosh, V Gautam, P Malhotra, P Ray - Microbial pathogenesis, 2017 - Elsevier
Acinetobacter baumannii has emerged as an important opportunistic pathogen mostly
causing nosocomial infections. The virulence factors of this important pathogen are largely …

[HTML][HTML] Acinetobacter baumannii Secretes Cytotoxic Outer Membrane Protein A via Outer Membrane Vesicles

JS Jin, SO Kwon, DC Moon, M Gurung, JH Lee, SI Kim… - PloS one, 2011 - journals.plos.org
Acinetobacter baumannii is an important nosocomial pathogen that causes a high morbidity
and mortality rate in infected patients, but pathogenic mechanisms of this microorganism …

Toll-like receptors 2 and 4 modulate pulmonary inflammation and host factors mediated by outer membrane vesicles derived from Acinetobacter baumannii

CR Marion, J Lee, L Sharma, KS Park, C Lee… - Infection and …, 2019 - Am Soc Microbiol
Pneumonia due to Gram-negative bacteria is associated with high mortality. Acinetobacter
baumannii is a Gram-negative bacterium that is associated with hospital-acquired and …

Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate

SO Kwon, YS Gho, JC Lee, SI Kim - FEMS microbiology letters, 2009 - academic.oup.com
The secretion of outer membrane vesicles (OMVs) is one of the major mechanisms by which
Gram-negative bacteria deliver effector molecules to host cells. Acinetobacter baumannii is …

[HTML][HTML] Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii

V Tiku, EM Kofoed, D Yan, J Kang, M Xu, M Reichelt… - Scientific reports, 2021 - nature.com
Acinetobacter baumannii is a highly antibiotic resistant Gram-negative bacterium that
causes life-threatening infections in humans with a very high mortality rate. A. baumannii is …

[HTML][HTML] Antibiotic treatment modulates protein components of cytotoxic outer membrane vesicles of multidrug-resistant clinical strain, Acinetobacter baumannii …

SH Yun, EC Park, SY Lee, H Lee, CW Choi, YS Yi… - Clinical proteomics, 2018 - Springer
Abstract Background Outer membrane vesicles (OMVs) of Acinetobacter baumannii are
cytotoxic and elicit a potent innate immune response. OMVs were first identified in A …