Tobramycin is commonly used to treat Pseudomonas aeruginosa lung infections in patients
with Cystic Fibrosis (CF). Tobramycin treatment leads to increased lung function and fewer …

Escherichia coli, as one of the gut microbiota, can evoke severe inflammatory diseases
including peritonitis and sepsis. Gram-negative bacteria including E. coli constitutively …

Background. Outer membrane protein A (OmpA) is a porin involved in Acinetobacter
baumannii pathogenesis. However, OmpA clinical implication in hospital-acquired infections …

Membrane vesicles (MVs) are small spherical structures (20–400 nm) produced by most
bacteria and have important biological functions including toxin delivery, signal transfer …

Almost all bacteria secrete spherical membranous nanoparticles, also referred to as
membrane vesicles (MVs). A variety of MV types exist, ranging from 20 to 400 nm in …

Abstract Background Zinc uptake-regulator (Zur)-regulated lipoprotein A (ZrlA) plays a role
in bacterial fitness and overcoming antimicrobial exposure in Acinetobacter baumannii. This …

Antimicrobial resistance (AMR) is a serious and most urgent global threat to human health.
AMR is one of today's biggest difficulties in the health system and has the potential to harm …

Klebsiella pneumoniae is a nosocomial pathogen and an important propagator of multidrug-
resistant (MDR) and extensively drug-resistant (XDR) strains. Like other Gram-negative …

Outer-membrane vesicles (OMVs) are spherical buds of the outer membrane filled with
periplasmic content and are commonly produced by Gram-negative bacteria. The production …

Bacteria use a variety of secreted virulence factors to manipulate host cells, thereby causing
significant morbidity and mortality. We report a mechanism for the long-distance delivery of …