The Acinetobacter baumannii 19606 OmpA Protein Plays a Role in Biofilm Formation on Abiotic Surfaces and in the Interaction of This Pathogen with Eukaryotic Cells

JA Gaddy, AP Tomaras, LA Actis - Infection and immunity, 2009 - Am Soc Microbiol
The ability of Acinetobacter baumannii to adhere to and persist on surfaces as biofilms could
be central to its pathogenicity. The production of pili and a biofilm-associated protein and the …

Acinetobacter baumannii Outer Membrane Protein A Induces Pulmonary Epithelial Barrier Dysfunction and Bacterial Translocation Through The TLR2/IQGAP1 Axis

W Zhang, H Zhou, Y Jiang, J He, Y Yao… - Frontiers in …, 2022 - frontiersin.org
Pulmonary epithelial barrier dysfunction is a critical pathophysiological process in
pneumonia and associated invasive infections, such as those caused by Acinetobacter …

[HTML][HTML] Bacterial outer membrane vesicle biogenesis: a new mechanism and its implications

S Roier, FG Zingl, F Cakar, S Schild - Microbial Cell, 2016 - ncbi.nlm.nih.gov
Outer membrane vesicle (OMV) release by Gram-negative bacteria has been observed and
studied for decades. First considered as a by-product of cell lysis, it soon became evident …

Outer membrane protein A inhibits the degradation of caspase-1 to regulate NLRP3 inflammasome activation and exacerbate the Acinetobacter baumannii pulmonary …

Y Li, C Peng, D Zhao, L Liu, B Guo, M Shi, Y Xiao… - Microbial …, 2021 - Elsevier
Abstract Acinetobacter baumannii (A. baumannii), one of the major pathogens that causes
severe nosocomial infections, is characterised by a high prevalence of drug resistance. It …

Role of the Vibrio cholerae Matrix Protein Bap1 in Cross-Resistance to Antimicrobial Peptides

M Duperthuy, AE Sjöström, D Sabharwal… - PLoS …, 2013 - journals.plos.org
Outer membrane vesicles (OMVs) that are released from Gram-negative pathogenic bacteria
can serve as vehicles for the translocation of effectors involved in infectious processes. In …

Host immunity and cellular responses to bacterial outer membrane vesicles

V Tiku, MW Tan - Trends in Immunology, 2021 - cell.com
All Gram-negative bacteria produce outer membrane vesicles (OMVs) which are minute
spherical structures emanating from the bacterial outer membrane. OMVs are primarily …

Vesiculation from Pseudomonas aeruginosa under SOS

R Maredia, N Devineni, P Lentz… - The Scientific World …, 2012 - Wiley Online Library
Bacterial infections can be aggravated by antibiotic treatment that induces SOS response
and vesiculation. This leads to a hypothesis concerning association of SOS with …

The discovery of the role of outer membrane vesicles against bacteria

S Combo, S Mendes, KM Nielsen, GJ da Silva… - Biomedicines, 2022 - mdpi.com
Gram-negative bacteria are intrinsically resistant to many commercialized antibiotics. The
outer membrane (OM) of Gram-negative bacteria prevents the entry of such antibiotics. Outer …

Bacterial outer membrane vesicles and immune modulation of the host

LA Charpentier, EF Dolben, MR Hendricks, DA Hogan… - Membranes, 2023 - mdpi.com
This article reviews the role of outer membrane vesicles (OMVs) in mediating the interaction
between Gram-negative bacteria and their human hosts. OMVs are produced by a diverse …

Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa

IA MacDonald, MJ Kuehn - Journal of bacteriology, 2013 - Am Soc Microbiol
As an opportunistic Gram-negative pathogen, Pseudomonas aeruginosa must be able to
adapt and survive changes and stressors in its environment during the course of infection …