Development and optimization of the novel fabrication method of highly macroporous chitosan/agarose/nanohydroxyapatite bone scaffold for potential regenerative …

P Kazimierczak, K Palka, A Przekora - Biomolecules, 2019 - mdpi.com
Bone scaffolds mimicking the three-dimensional bone structure are of essential importance
for bone regeneration. The aim of this study was to develop and optimize the production …

Novel synthesis method combining a foaming agent with freeze-drying to obtain hybrid highly macroporous bone scaffolds

P Kazimierczak, A Benko, K Palka, C Canal… - Journal of Materials …, 2020 - Elsevier
Three-dimensional macroporous scaffolds are commonly used in bone tissue engineering
applications since they provide sufficient space for cell migration and proliferation …

Novel chitosan/agarose/hydroxyapatite nanocomposite scaffold for bone tissue engineering applications: Comprehensive evaluation of biocompatibility and …

P Kazimierczak, A Benko, M Nocun… - International journal of …, 2019 - Taylor & Francis
Background Nanocomposites produced by reinforcement of polysaccharide matrix with
nanoparticles are widely used in engineering of biomaterials. However, clinical applications …

Development of gelatin/carboxymethyl chitosan/nano-hydroxyapatite composite 3D macroporous scaffold for bone tissue engineering applications

S Maji, T Agarwal, J Das, TK Maiti - Carbohydrate polymers, 2018 - Elsevier
The present study delineates a relatively simpler approach for fabrication of a macroporous
three-dimensional scaffold for bone tissue engineering. The novelty of the work is to obtain a …

Fabrication and characterization of novel nano-biocomposite scaffold of chitosan–gelatin–alginate–hydroxyapatite for bone tissue engineering

C Sharma, AK Dinda, PD Potdar, CF Chou… - Materials Science and …, 2016 - Elsevier
A novel nano-biocomposite scaffold was fabricated in bead form by applying simple foaming
method, using a combination of natural polymers–chitosan, gelatin, alginate and a …

Design, synthesis, and fabrication of chitosan/hydroxyapatite composite scaffold for use as bone replacement tissue by sol–gel method

A Farazin, AH Ghasemi - … of Inorganic and Organometallic Polymers and …, 2022 - Springer
Injuries or bone defects are phenomena that are harmful to human health. In the field of
bone scaffold tissue engineering, hydroxyapatite nanoparticles have been considered due …

Development of gelatin-chitosan-hydroxyapatite based bioactive bone scaffold with controlled pore size and mechanical strength

K Maji, S Dasgupta, B Kundu… - Journal of Biomaterials …, 2015 - Taylor & Francis
Hydroxyapatite–chitosan/gelatin (HA: Chi: Gel) nanocomposite scaffold has potential to
serve as a template matrix to regenerate extra cellular matrix of human bone. Scaffolds with …

Fabrication of cancellous biomimetic chitosan‐based nanocomposite scaffolds applying a combinational method for bone tissue engineering

Z Jamalpoor, H Mirzadeh, MT Joghataei… - … research Part A, 2015 - Wiley Online Library
The aim of this study was to mimic the specific structure of bone and fabricate a biomimetic
nano‐hydroxyapatite (HA)/chitosan (Cs)/gelatin scaffolds using combination of particle …

Chitosan scaffolds with mesoporous hydroxyapatite and mesoporous bioactive glass

AS Pádua, L Figueiredo, JC Silva, JP Borges - Progress in Biomaterials, 2023 - Springer
Bone regeneration is one of the most well-known fields in tissue regeneration. The major
focus concerns polymeric/ceramic composite scaffolds. In this work, several composite …

Biological response to macroporous chitosan-agarose bone scaffolds comprising Mg-and Zn-doped nano-hydroxyapatite

P Kazimierczak, J Kolmas, A Przekora - International Journal of Molecular …, 2019 - mdpi.com
Modification of implantable scaffolds with magnesium and zinc for improvement of bone
regeneration is a growing trend in the engineering of biomaterials. The aim of this study was …