The relationship between atrial fibrillation and NLRP3 inflammasome: a gut microbiota perspective
Y Xing, L Yan, X Li, Z Xu, X Wu, H Gao, Y Chen… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) is a common clinical arrhythmia whose pathogenesis has not been fully
elucidated, and the inflammatory response plays an important role in the development of AF …
elucidated, and the inflammatory response plays an important role in the development of AF …
Gut microbiota dysbiosis promotes age-related atrial fibrillation by lipopolysaccharide and glucose-induced activation of NLRP3-inflammasome
Y Zhang, S Zhang, B Li, Y Luo, Y Gong… - Cardiovascular …, 2022 - academic.oup.com
Aims Ageing is the most significant contributor to the increasing prevalence of atrial
fibrillation (AF). The gut microbiota dysbiosis is involved in age-related diseases. However …
fibrillation (AF). The gut microbiota dysbiosis is involved in age-related diseases. However …
Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation
C Yao, T Veleva, L Scott Jr, S Cao, L Li, G Chen… - Circulation, 2018 - Am Heart Assoc
Background: Atrial fibrillation (AF) is frequently associated with enhanced inflammatory
response. The NLRP3 (NACHT, LRR, and PYD domain containing protein 3) inflammasome …
response. The NLRP3 (NACHT, LRR, and PYD domain containing protein 3) inflammasome …
[PDF][PDF] Enhanced activation of inflammasome promotes atrial fibrillation
Background: Inflammation has been associated with the progression of atrial fibrillation (AF)
in patients, while the underlying molecular mechanisms remain elusive. It is known that a …
in patients, while the underlying molecular mechanisms remain elusive. It is known that a …
Targeting the NLRP3 inflammasome signalling for the management of atrial fibrillation
Inflammatory signalling via the nod‐like receptor (NLR) family pyrin domain‐containing
protein‐3 (NLRP3) inflammasome has recently been implicated in the pathophysiology of …
protein‐3 (NLRP3) inflammasome has recently been implicated in the pathophysiology of …
Inflammasomes and proteostasis novel molecular mechanisms associated with atrial fibrillation
N Li, BJJM Brundel - Circulation research, 2020 - Am Heart Assoc
Atrial fibrillation (AF), the most common progressive and age-related cardiac arrhythmia,
affects millions of people worldwide. AF is associated with common risk factors, including …
affects millions of people worldwide. AF is associated with common risk factors, including …
Activation of NLRP3 inflammasome promotes atrial fibrillation
Introduction: Sterile inflammation is frequently observed in patients with atrial fibrillation (AF),
the most common cardiac arrhythmia. However, whether inflammation signaling plays a …
the most common cardiac arrhythmia. However, whether inflammation signaling plays a …
Inflammasome Signaling in Atrial Fibrillation: JACC State-of-the-Art Review
As the most prevalent form of arrhythmia, atrial fibrillation (AF) increases the risk of heart
failure, thromboembolism, and stroke, contributing to the raising mortality and morbidity in …
failure, thromboembolism, and stroke, contributing to the raising mortality and morbidity in …
Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology
Inflammation has been implicated in atrial fibrillation (AF), a very common and clinically
significant cardiac rhythm disturbance, but its precise role remains poorly understood. Work …
significant cardiac rhythm disturbance, but its precise role remains poorly understood. Work …
Research progress on the relationship between NLRP3 inflammasome and atrial fibrillation
YM Wang, W Wang, YF Tian… - Zhonghua xin xue …, 2021 - pubmed.ncbi.nlm.nih.gov
炎症在心房颤动 (房颤) 的发生, 发展过程中有重要作用. 炎症小体是先天免疫的重要组成部分,
参与多种病理生理学过程. NLRP3 炎症小体能够在多种类型的细胞中表达并发挥关键作用 …
参与多种病理生理学过程. NLRP3 炎症小体能够在多种类型的细胞中表达并发挥关键作用 …