Mitochondria in ovarian aging and reproductive longevity
Mitochondrial dysfunction is one of the hallmarks of aging. Consistently mitochondrial DNA
(mtDNA) copy number and function decline with age in various tissues. There is increasing …
(mtDNA) copy number and function decline with age in various tissues. There is increasing …
Mitochondrial dysfunction and ovarian aging
Mitochondria are double‐membrane‐bound organelles that are responsible for the
generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in …
generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in …
Ovarian ageing: the role of mitochondria in oocytes and follicles
P May-Panloup, L Boucret… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND There is a great inter-individual variability of ovarian ageing, and almost
20% of patients consulting for infertility show signs of premature ovarian ageing. This …
20% of patients consulting for infertility show signs of premature ovarian ageing. This …
[HTML][HTML] Mitochondria in oocyte aging: current understanding
D Zhang, D Keilty, ZF Zhang… - Facts, views & vision in …, 2017 - ncbi.nlm.nih.gov
The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …
factories for cells, are found in high numbers in oocytes, as they provide the energy for …
Mitochondrial dysfunction and ovarian aging
I Kasapoğlu, E Seli - Endocrinology, 2020 - academic.oup.com
As women delay childbearing because of demographic and socioeconomic trends,
reproductive aging and ensuing ovarian dysfunction become increasingly more prevalent …
reproductive aging and ensuing ovarian dysfunction become increasingly more prevalent …
[HTML][HTML] Mitochondria: Their relevance during oocyte ageing
J van der Reest, GN Cecchino, MC Haigis… - Ageing research …, 2021 - Elsevier
The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …
The contribution of mitochondrial function to reproductive aging
Purpose The number of women attempting to conceive between the ages of 36 and 44 has
increased significantly in the last decade. While it is well established that women's …
increased significantly in the last decade. While it is well established that women's …
Mitochondria: participation to infertility as source of energy and cause of senescence
M Benkhalifa, YJ Ferreira, H Chahine, N Louanjli… - The international journal …, 2014 - Elsevier
Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …
Reproductive aging is associated with changes in oocyte mitochondrial dynamics, function, and mtDNA quantity
Mitochondria affect numerous aspects of mammalian reproduction. We investigated whether
the decrease in oocyte quality associated with aging is related to altered mitochondria …
the decrease in oocyte quality associated with aging is related to altered mitochondria …
The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights
GN Cecchino, E Seli, ELA da Motta… - Reproductive …, 2018 - Elsevier
Mitochondria have been implicated as key factors regulating female reproductive processes.
Notable progress has been made in determining the role of mitochondria with respect to …
Notable progress has been made in determining the role of mitochondria with respect to …