Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

Mitochondria play an essential role in generating energy for embryo development and
maintaining embryo metabolism through key cellular functions including ion homeostasis …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

It is likely that there is an association between the fitness of mitochondria and their ability to
support normal cellular function. Oocytes are greatly enriched in the number of mitochondria …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

Mitochondria have been implicated as key factors regulating female reproductive processes.
Notable progress has been made in determining the role of mitochondria with respect to …

Mitochondria play a primary role in cellular energetic metabolism, homeostasis, and death.
They possess their own multicopy genome, which is maternally transmitted. Mitochondria …

Oocyte quality has long been considered as a main limiting factor for in vitro fertilization
(IVF). In the past decade, extensive observations demonstrated that the mitochondrion plays …

The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Mitochondrial dysfunction is widely implicated in various human diseases, through
mechanisms that go beyond mitochondria's well-established role in energy generation …