Mitochondria are critical subcellular organelles that produce most of the adenosine
triphosphate (ATP) as the energy source for most eukaryotic cells. Moreover, recent findings …

Highlights•Dysregulation of mitochondrial metabolism is a hallmark of cancer development.•
Nanoparticles (NPs) enable the efficient and targeted delivery of mitochondrial agents.•NPs …

Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Nanosystems for targeted delivery of cargos to mitochondria for cancer …

Nanomedicines have been designed and developed to deliver anticancer drugs or exert
anticancer therapy more selectively to tumor sites. Recent investigations have gone beyond …

Any variation in normal cellular function results in mitochondrial dysregulation that occurs in
several diseases, including cancer. Such processes as oxidative stress, metabolism …

The early understanding of mitochondria posited that they were 'innocent organelles' solely
devoted to energy production and utilisation. Intriguingly, recent findings have outlined in …

Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

Mitochondria are a major intracellular organelle for drug targeting due to its functional roles
in cellular metabolism and cell signaling for proliferation and cell death. Mitochondria …

Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …