Mitochondrial dysfunctions are recognized as major factors for various diseases including
cancer, cardiovascular diseases, diabetes, neurological disorders, and a group of diseases …

Mitochondria have recently emerged as novel targets for cancer therapy due to its important
roles in fundamental cellular function. Discovery of new chemotherapeutic agents that allow …

Mitochondrial dysfunction acts as a common pathogenetic mechanism in several acute and
chronic liver diseases, such as Alcoholic and Non-Alcoholic Fatty Liver Disease (NAFLD) …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

The application of engineered bacteria-based drug delivery vehicles to treat cancer has
been practiced for more than a century. Mitochondria, evolutionarily originated from bacteria …

The field of mitochondrial research is currently among the fastest growing disciplines in
biomedicine. Approximately 12,000 articles on mitochondria have been published since the …

Mitochondria are organelles controlling adenosine triphosphate (ATP) generation, redox
homeostasis, metabolic signaling, and apoptotic pathways. Although glycolysis was …

There have been numerous efforts to develop targeted therapies for treating cancer. The
non-specificity of'classical'cytotoxic chemotherapy drugs and drug resistance remain major …

Mitochondria are the powerhouse of cells. They are vital organelles that maintain cellular
function and metabolism. Dysfunction of mitochondria results in various diseases with a …

Mitochondria play a central role in cancer progression and tumor metastasis, and
nanomedicines targeting mitochondria have emerged as a promising strategy for tumor …