Comparison of chemotherapy effects on mechanical sensitivity and food-maintained operant responding in male and female rats
LP Legakis, CM Diester, EA Townsend… - Behavioural …, 2020 - journals.lww.com
Chemotherapies of varying classes often cause neuropathy and debilitating chemotherapy-
induced neuropathic pain sufficient to limit treatment and reduce quality of life for many …
induced neuropathic pain sufficient to limit treatment and reduce quality of life for many …
Effects of chemotherapy on operant responding for palatable food in male and female mice
JA Meade, AN Fowlkes, MJ Wood… - Behavioural …, 2021 - journals.lww.com
Patients treated with cancer chemotherapeutics frequently report chemotherapy-induced
peripheral neuropathy (CIPN), changes in mood (depression and anxiety) and functional …
peripheral neuropathy (CIPN), changes in mood (depression and anxiety) and functional …
Combination chemotherapy in rodents: a model for chemotherapy-induced neuropathic pain and pharmacological screening
Akhilesh, A Uniyal, A Mehta, V Tiwari - Metabolic Brain Disease, 2024 - Springer
Chemotherapy-induced neuropathic pain (CINP) remains a therapeutic challenge, with no
US-FDA approved drugs or effective treatments available. Despite significant progress in …
US-FDA approved drugs or effective treatments available. Despite significant progress in …
Repeated morphine produces sensitization to reward and tolerance to antiallodynia in male and female rats with chemotherapy-induced neuropathy
LP Legakis, SS Negus - Journal of Pharmacology and Experimental …, 2018 - ASPET
Paclitaxel is a cancer chemotherapy drug with adverse effects that include chemotherapy-
induced neuropathic pain (CINP) as well as depression of behavior and mood. In the clinical …
induced neuropathic pain (CINP) as well as depression of behavior and mood. In the clinical …
Optimization and pharmacological characterization of a refined cisplatin-induced rat model of peripheral neuropathic pain
Chemotherapy-induced peripheral neuropathy (CIPN) is the major dose-limiting side-effect
of many front-line anticancer drugs. This study was designed to establish and …
of many front-line anticancer drugs. This study was designed to establish and …
Persistent hyperalgesia in the cisplatin-treated mouse as defined by threshold measures, the conditioned place preference paradigm, and changes in dorsal root …
HJ Park, JA Stokes, E Pirie, J Skahen… - Anesthesia & …, 2013 - journals.lww.com
BACKGROUND: Painful neuropathy is a dose-limiting side effect in cancer chemotherapy.
To characterize this phenomenon, we examined pain behavior and analgesic actions in a …
To characterize this phenomenon, we examined pain behavior and analgesic actions in a …
Gender differences in a mouse model of chemotherapy-induced neuropathic pain
H Naji-Esfahani, G Vaseghi, L Safaeian… - Laboratory …, 2016 - journals.sagepub.com
Chemotherapy-induced neuropathic pain is one of the major problems for cancer patients.
Although paclitaxel and cisplatin are widely used in women, most laboratory studies of …
Although paclitaxel and cisplatin are widely used in women, most laboratory studies of …
Animal models of chemotherapy-evoked painful peripheral neuropathies
N Authier, D Balayssac, F Marchand, B Ling… - …, 2009 - Springer
This review examines recent preclinical research on toxic peripheral neuropathy and
potential therapeutic developments. Chemotherapy-induced peripheral neurotoxicity is a …
potential therapeutic developments. Chemotherapy-induced peripheral neurotoxicity is a …
Attenuation of mechanical allodynia by clinically utilized drugs in a rat chemotherapy-induced neuropathic pain model
JJ Lynch III, CL Wade, CM Zhong, JP Mikusa, P Honore - Pain, 2004 - Elsevier
Chemotherapy-induced peripheral neuropathy is a common, dose-limiting side effect of
cancer chemotherapeutic agents, including the vinca alkaloids such as vincristine. The …
cancer chemotherapeutic agents, including the vinca alkaloids such as vincristine. The …
Chemotherapy-induced peripheral neuropathic pain and rodent models
A Hama, H Takamatsu - … Formerly Current Drug Targets-CNS & …, 2016 - ingentaconnect.com
Painful peripheral neuropathies resulting from cancer chemotherapy treatment is frequently
dose-dependent and may diminish following dose reduction or termination of chemotherapy …
dose-dependent and may diminish following dose reduction or termination of chemotherapy …