Background Airway and systemic eosinophilia are important treatable traits in both severe
asthma and COPD. The molecular basis of eosinophilia in COPD is poorly understood but …

To the Editor, Type 2 (T2) inflammation in asthma encompasses the presence of
eosinophilic inflammation and/or selected cytokines including interleukin (IL)-13. Some …

Background Whether the clinical or pathophysiologic significance of the “treatable trait” high
blood eosinophil count in COPD is the same as for asthma remains controversial. We sought …

COPD is a significant cause of morbidity and mortality. In some patients with COPD,
eosinophils contribute to inflammation that promotes airway obstruction; approximately a …

Objective: To investigate serum and sputum cytokine profiles in asthma and chronic
obstructive pulmonary disorder (COPD). Methods: Clinical characteristics, blood and sputum …

Background Eosinophilic airway inflammation in patients with chronic obstructive pulmonary
disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting …

The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are
common affecting over 500 million people worldwide and causing substantial morbidity and …

Background and objective There is less understanding of phenotypes and disease burden
in asthma‐COPD overlap (ACO) than either disease alone. Blood eosinophils may help …

Background Eosinophilic airway inflammation can predict the exacerbation of asthma, and
we can improve the management of asthma by monitoring the eosinophilic airway …

Background: Asthma and COPD are complex, heterogeneous conditions comprising a wide
range of phenotypes, some of which are refractory to currently available treatments …