MWCNTs/PEDOT: PSS nanocomposites-modified microelectrode array for spatial dynamics recording of epileptic discharges in multi-subregion of hippocampal slice

E He, S Xu, G Xiao, Y Dai, X Li, Y Song, F Gao… - Sensors and Actuators B …, 2021 - Elsevier
The acute hippocampal slice is useful for understanding how epilepsy spatially initiates,
propagates, and terminates in the hippocampus, which is vital to study the epileptic …

PDMS–parylene hybrid, flexible micro-ECoG electrode array for spatiotemporal mapping of epileptic electrophysiological activity from multicortical brain regions

X Li, Y Song, G Xiao, E He, J Xie, Y Dai… - ACS Applied Bio …, 2021 - ACS Publications
Epilepsy detection and focus location are urgent issues that need to be solved in epilepsy
research. A cortex conformable and fine spatial accuracy electrocorticogram (ECoG) sensor …

In situ detection of neurotransmitters and epileptiform electrophysiology activity in awake mice brains using a nanocomposites modified microelectrode array

G Xiao, S Xu, Y Song, Y Zhang, Z Li, F Gao… - Sensors and Actuators B …, 2019 - Elsevier
A novel nanocomposites modified microelectrode array (MEA) was designed and fabricated
for in situ detection of neurotransmitters (glutamate and dopamine) and electrophysiology …

PtNPs/RGO-GluOx/MPD directionally electroplated dual-mode microelectrode arrays for detecting the synergistic relationship between the cortex and hippocampus of …

J Xie, Y Dai, Y Xing, Y Wang, G Yang, E He, Z Xu… - ACS …, 2023 - ACS Publications
Precise and directional couplings of functional nanomaterials with implantable
microelectrode arrays (IMEAs) are critical for the manufacture of sensitive enzyme-based …

Flexible electrocorticography electrode array for epileptiform electrical activity recording under glutamate and GABA modulation on the primary somatosensory cortex …

X Li, Y Song, G Xiao, J Xie, Y Dai, Y Xing, E He… - Micromachines, 2020 - mdpi.com
Epilepsy is a common neurological disorder. There is still a lack of methods to accurately
detect cortical activity and locate lesions. In this work, a flexible electrocorticography (ECoG) …

In vivo microelectrode arrays for detecting multi-region epileptic activities in the hippocampus in the latent period of rat model of temporal lobe epilepsy

Y Dai, Y Song, J Xie, S Xu, X Li, E He, H Yin, X Cai - Micromachines, 2021 - mdpi.com
Temporal lobe epilepsy (TLE) is a form of refractory focal epilepsy, which includes a latent
period and a chronic period. Microelectrode arrays capable of multi-region detection of …

Cellular-scale microelectrode arrays to monitor movement-related neuron activities in the epileptic hippocampus of awake mice

G Xiao, Y Song, Y Zhang, Y Xing, S Xu… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Objective: Epilepsy affects 50 million people worldwide and its pathogenesis is still
unknown. In particular, the movement-related neural activities involving glutamate (Glu) and …

High-throughput PEDOT: PSS/PtNPs-modified microelectrode array for simultaneous recording and stimulation of hippocampal neuronal networks in gradual learning …

S Xu, Y Deng, J Luo, E He, Y Liu, K Zhang… - … Applied Materials & …, 2022 - ACS Publications
When it comes to mechanisms of brain functions such as learning and memory mediated by
neural networks, existing multichannel electrophysiological detection and regulation …

Bio-electrochemical microelectrode arrays for glutamate and electrophysiology detection in hippocampus of temporal lobe epileptic rats

Z Li, Y Song, G Xiao, F Gao, S Xu, M Wang… - Analytical …, 2018 - Elsevier
Abstract Temporal Lobe Epilepsy (TLE) is a chronic neurological disorder, characterized by
sudden, repeated and transient central nervous system dysfunction. For better …

In situ real-time monitoring of glutamate and electrophysiology from cortex to hippocampus in mice based on a microelectrode array

X Fan, Y Song, Y Ma, S Zhang, G Xiao, L Yang, H Xu… - Sensors, 2016 - mdpi.com
Changes in the structure and function of the hippocampus contribute to epilepsy,
schizophrenia and other neurological or mental disorders of the brain. Since the function of …