The molecular characterization and protective efficacy of microneme 3 of Eimeria mitis in chickens

X Huang, J Liu, D Tian, W Li, Z Zhou, J Huang… - Veterinary …, 2018 - Elsevier
E. mitis is ubiquitous in clinical coccidiosis caused by mixed infection of Eimeria species and
the infection by E. mitis usually significantly impairs productivity of the infected chickens. To …

The molecular characterization and immune protection of microneme 2 of Eimeria acervulina

ZC Zhang, LR Liu, JW Huang, S Wang, MM Lu… - Veterinary …, 2016 - Elsevier
Eimeria acervulina (E. acervulina) is an intestinal protozoon and few of its antigen genes
were researched. In this study, the gene of E. acervulina microneme protein 2 (EaMIC2) was …

Specific EtMIC3-binding peptides inhibit Eimeria tenella sporozoites entry into host cells

W Chen, C Ma, G Li, Z Jia, X Yang, X Pan, D Ma - Veterinary Research, 2021 - Springer
Avian coccidiosis caused by Eimeria leads to huge economic losses on the global poultry
industry. In this study, microneme adhesive repeat regions (MARR) bc1 of E. tenella …

Transgenic Eimeria mitis expressing chicken interleukin 2 stimulated higher cellular immune response in chickens compared with the wild-type parasites

Z Li, X Tang, J Suo, M Qin, G Yin, X Liu… - Frontiers in …, 2015 - frontiersin.org
Chicken coccidiosis, caused by Eimeria sp., occurs in almost all poultry farms and causes
huge economic losses in the poultry industry. Although this disease could be controlled by …

An Eimeria maxima Antigen: Its Functions on Stimulating Th1 Cytokines and Protective Efficacy Against Coccidiosis

C Chen, Y Zhang, J Liu, M Wang, M Lu, L Xu… - Frontiers in …, 2022 - frontiersin.org
A consensus is that the Th1 immune response plays a predominant role against avian
coccidiosis. Therefore, an antigen with the ability to induce Th1 cytokine responses is an …

Pichia pastoris expressed EtMic2 protein as a potential vaccine against chicken coccidiosis

J Zhang, P Chen, H Sun, Q Liu, L Wang, T Wang… - Veterinary …, 2014 - Elsevier
Chicken coccidiosis caused by Eimeria species leads to tremendous economic losses to the
avian industry worldwide. Identification of parasite life cycle specific antigens is a critical step …

[HTML][HTML] Evaluation of 4 merozoite antigens as candidate vaccines against Eimeria tenella infection

X Song, X Yang, T Zhang, J Liu, Q Liu - Poultry Science, 2021 - Elsevier
Coccidiosis, caused by parasites of the genus Eimeria, is one of the most widespread and
economically detrimental diseases in the global poultry industry. Because the merozoite …

[HTML][HTML] Molecular characterization and protective efficacy of the microneme 2 protein from Eimeria tenella

M Yan, X Cui, Q Zhao, S Zhu, B Huang, L Wang… - Parasite, 2018 - ncbi.nlm.nih.gov
Microneme proteins play an important role in the adherence of apicomplexan parasites to
host cells during the invasion process. In this study, the microneme 2 protein from the …

Identification and immunogenicity of microneme protein 2 (EbMIC2) of Eimeria brunetti

TD Hoan, Z Zhang, J Huang, R Yan, X Song… - Experimental …, 2016 - Elsevier
There have been only a few antigen genes of Eimeria brunetti reported up to now. In this
study, the gene encoding the microneme protein 2 (EbMIC2) was isolated from oocysts of E …

The microneme adhesive repeat domain of MIC3 protein determined the site specificity of Eimeria acervulina, Eimeria maxima, and Eimeria mitis

Y Zhang, M Lu, Z Zhang, X Huang, J Huang… - Frontiers in …, 2023 - frontiersin.org
Understanding the determinants of host and tissue tropisms among parasites of veterinary
and medical importance has long posed a substantial challenge. Among the seven species …