Novel chitosan/agarose/hydroxyapatite nanocomposite scaffold for bone tissue engineering applications: Comprehensive evaluation of biocompatibility and …

P Kazimierczak, A Benko, M Nocun… - International journal of …, 2019 - Taylor & Francis
Background Nanocomposites produced by reinforcement of polysaccharide matrix with
nanoparticles are widely used in engineering of biomaterials. However, clinical applications …

Biomimetic chitosan–nanohydroxyapatite composite scaffolds for bone tissue engineering

WW Thein-Han, RDK Misra - Acta biomaterialia, 2009 - Elsevier
We describe a comparative assessment of the structure–property–process relationship of
three-dimensional chitosan–nanohydroxyapatite (nHA) and pure chitosan scaffolds in …

Development and optimization of the novel fabrication method of highly macroporous chitosan/agarose/nanohydroxyapatite bone scaffold for potential regenerative …

P Kazimierczak, K Palka, A Przekora - Biomolecules, 2019 - mdpi.com
Bone scaffolds mimicking the three-dimensional bone structure are of essential importance
for bone regeneration. The aim of this study was to develop and optimize the production …

Chitosan/hydroxyapatite nanocomposite scaffolds to modulate osteogenic and inflammatory response

A Soriente, I Fasolino… - … Research Part A, 2022 - Wiley Online Library
Considerable attention has been given to the use of chitosan (CS)‐based materials
reinforced with inorganic bioactive signals such as hydroxyapatite (HA) to treat bone defects …

Characterization and biocompatibility of nanohybrid scaffold prepared via in situ crystallization of hydroxyapatite in chitosan matrix

J Chen, K Nan, S Yin, Y Wang, T Wu… - Colloids and Surfaces B …, 2010 - Elsevier
Hydroxyapatite (HAP) precursor solution was first mixed with an acetic acid chitosan (CS)
solution. The mixture was then lyophilized to form the original scaffold, which stored the HAP …

Development of porous and antimicrobial CTS–PEG–HAP–ZnO nano-composites for bone tissue engineering

A Bhowmick, N Pramanik, PJ Manna, T Mitra… - RSC …, 2015 - pubs.rsc.org
Herein, we have developed hybrid nanocomposites of chitosan, poly (ethylene glycol) and
nano-hydroxyapatite–zinc oxide with interconnected macroporous structures for bone tissue …

Comparative investigation of porous nano-hydroxyapaptite/chitosan, nano-zirconia/chitosan and novel nano-calcium zirconate/chitosan composite scaffolds for their …

B Gaihre, AC Jayasuriya - Materials science and engineering: C, 2018 - Elsevier
Zirconium (Zr) based bioceramic nanoparticles, as the filler material to chitosan (CS), for the
development of composite scaffolds are less studied compared to hydroxyapatite …

Development of new graphene oxide incorporated tricomponent scaffolds with polysaccharides and hydroxyapatite and study of their osteoconductivity on MG-63 cell …

R Rajesh, YD Ravichandran - RSC Advances, 2015 - pubs.rsc.org
Regenerative medicine witnessed a paradigm shift from synthetic implants and tissue grafts
to a tissue engineering approach that incorporates biodegradable, bioceramic composite …

Biological response to macroporous chitosan-agarose bone scaffolds comprising Mg-and Zn-doped nano-hydroxyapatite

P Kazimierczak, J Kolmas, A Przekora - International Journal of Molecular …, 2019 - mdpi.com
Modification of implantable scaffolds with magnesium and zinc for improvement of bone
regeneration is a growing trend in the engineering of biomaterials. The aim of this study was …

[HTML][HTML] Bone regeneration using bio-nanocomposite tissue reinforced with bioactive nanoparticles for femoral defect applications in medicine

MA Maghsoudlou, E Nassireslami… - Avicenna Journal of …, 2020 - ncbi.nlm.nih.gov
Background: In recent years, the method of constructing and evaluating the properties of
polymer nanocomposite and bioactive ceramics in tissue engineering such as …