Alpha-linolenic acid intake and 10-year incidence of coronary heart disease and stroke in 20,000 middle-aged men and women in the Netherlands

J de Goede, WMM Verschuren, JMA Boer… - PLoS …, 2011 - journals.plos.org
Background Whether intake of alpha-linolenic acid (ALA), the plant-derived n-3
polyunsaturated fatty acid (PUFA), could prevent cardiovascular diseases is not yet clear …

[HTML][HTML] α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis

A Pan, M Chen, R Chowdhury, JHY Wu, Q Sun… - The American journal of …, 2012 - Elsevier
Background: Prior studies of α-linolenic acid (ALA), a plant-derived omega-3 (n-3) fatty acid,
and cardiovascular disease (CVD) risk have generated inconsistent results. Objective: We …

[HTML][HTML] Dietary intake and adipose tissue content of α-linolenic acid and risk of myocardial infarction: a Danish cohort study

CS Bork, MU Jakobsen, S Lundbye-Christensen… - The American journal of …, 2016 - Elsevier
Background: Intake of the plant-derived ω-3 (n–3) fatty acid α-linolenic acid (ALA, 18: 3; n–3)
may reduce coronary heart disease (CHD) risk, but the results of previous studies have been …

[HTML][HTML] Dietary α-linolenic acid, linoleic acid, and n–3 long-chain PUFA and risk of ischemic heart disease

MS Vedtofte, MU Jakobsen, L Lauritzen… - The American journal of …, 2011 - Elsevier
Background: n− 3 (omega-3) PUFA has been proposed as having health-promoting effects,
primarily in relation to ischemic heart disease (IHD). Whether these benefits can be …

[HTML][HTML] Dietary intake of α-linolenic acid is not appreciably associated with risk of ischemic stroke among middle-aged Danish men and women

CS Bork, SK Venø, S Lundbye-Christensen… - The Journal of …, 2018 - Elsevier
Background Intake of the plant-derived omega-3 (n–3) fatty acid α-linolenic acid (ALA) may
reduce the risk of ischemic stroke. Objective We have investigated the associations between …

[HTML][HTML] α-Linolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: the Zutphen Elderly Study

CM Oomen, MC Ocké, EJM Feskens, FJ Kok… - The American journal of …, 2001 - Elsevier
Background: Data on the relation between α-linolenic acid intake and coronary artery
disease (CAD) are limited. Other dietary components appear to modify the reported relation …

Does alpha-linolenic acid intake reduce the risk of coronary heart disease? A review of the evidence

D Mozaffarian - Alternative therapies in health and medicine, 2005 - search.proquest.com
Alpha-linolenic acid (ALA) is an n-3 polyunsaturated fatty acid found mainly in plant sources,
including flaxseed oil, canola oil, and walnuts. Although substantial evidence indicates that …

Association between the intake of α-linolenic acid and the risk of CHD

MS Vedtofte, MU Jakobsen, L Lauritzen… - British journal of …, 2014 - cambridge.org
The intake of the mainly plant-derived n-3 PUFA α-linolenic acid (ALA) has been reported to
be associated with a lower risk of CHD. However, the results have been inconsistent …

Plasma phospholipid and dietary α-linolenic acid, mortality, CHD and stroke: the Cardiovascular Health Study

AM Fretts, D Mozaffarian, DS Siscovick… - British journal of …, 2014 - cambridge.org
Previous studies have suggested that long-chain n-3 fatty acids derived from seafood are
associated with a lower risk of mortality, CHD and stroke. Whether α-linolenic acid (ALA, 18 …

[HTML][HTML] Impact of α-linolenic acid, the vegetable ω-3 fatty acid, on cardiovascular disease and cognition

A Sala-Vila, J Fleming, P Kris-Etherton, E Ros - Advances in Nutrition, 2022 - Elsevier
Given the evidence of the health benefits of plant-based diets and long-chain n–3 (ω-3) fatty
acids, there is keen interest in better understanding the role of α-linolenic acid (ALA), a plant …