The molecular environment of the host can have profound effects on the behavior of resident
bacterial species. We recently established how the sensing and response of …

The ability of any organism to sense and respond to challenges presented in the
environment is critically important for promoting or restricting colonization of specific sites …

Sensing environmental stimuli is critically important for bacteria when faced with the
multitude of adversities presented within the host. Responding appropriately to these signals …

Escherichia coli comprise a diverse array of both commensals and niche-specific
pathotypes. The ability to cause disease results from both carriage of specific virulence …

We recently discovered that exposure of enterohemorrhagic Escherichia coli (EHEC) to d-
serine resulted in accumulation of this unusual amino acid, induction of the SOS regulon …

Appropriate interpretation of environmental signals facilitates niche specificity in pathogenic
bacteria. However, the responses of niche-specific pathogens to common host signals are …

The emergence of multidrug-resistant pathogens presents a global challenge for treating
and preventing disease spread through zoonotic transmission. The water and foodborne …

Escherichia coli associates with humans early in life and can occupy several body niches
either as a commensal in the gut and vagina, or as a pathogen in the urinary tract. As such …

Escherichia coli is a commensal of the gastrointestinal tract of humans and animals, and a
leading cause of gastroenteritis, bloodstream, and urinary tract infection, among others …

Ecologically beneficial traits in bacteria are encoded by intrinsic and horizontally acquired
genes. However, such traits are not universal, and the highly mosaic nature of bacterial …