Neurophysiological adaptations to spaceflight and simulated microgravity

AB Stella, M Ajčević, G Furlanis, P Manganotti - Clinical Neurophysiology, 2021 - Elsevier
Abstract Changes in physiological functions after spaceflight and simulated spaceflight
involve several mechanisms. Microgravity is one of them and it can be partially reproduced …

Functional involvement of central nervous system at high altitude

G Miscio, E Milano, J Aguilar, G Savia, G Foffani… - Experimental brain …, 2009 - Springer
Acute mountain sickness is a common discomfort experienced by unacclimatized persons
on ascent to high altitude. We tested the hypothesis that exposure to high altitude affects …

A temporal study on learning and memory at high altitude in two ethnic groups

K Ray, K Kishore, P Vats, D Bhattacharyya… - … Altitude Medicine & …, 2019 - liebertpub.com
Introduction: Cognitive function has been compromised during high-altitude (HA) exposure
due to slowing of mental processing. Materials and Methods: A total of 20 Indian and 20 …

Changes in prefrontal cerebral oxygenation and microvascular blood volume in hypoxia and possible association with acute mountain sickness

G Manferdelli, M Marzorati, C Easton… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? The role of the cerebral
haemodynamic response to either normobaric or hypobaric hypoxia in people susceptible to …

Resting-state neuronal activity and functional connectivity changes in the visual cortex after high altitude exposure: a longitudinal study

X Zhang, T Kang, Y Liu, F Yuan, M Li, J Lin, J Zhang - Brain Sciences, 2022 - mdpi.com
Damage to the visual cortex structures after high altitude exposure has been well clarified.
However, changes in the neuronal activity and functional connectivity (FC) of the visual …

'Ome'on the range: update on high-altitude acclimatization/adaptation and disease

Y Luo, Y Wang, H Lu, Y Gao - Molecular BioSystems, 2014 - pubs.rsc.org
The main physiological challenge in high-altitude plateau environments is hypoxia. When
people living in a plain environment migrate to the plateau, they face the threat of hypoxia …

Cognitive performance in high-altitude Andean residents compared with low-altitude populations: from childhood to older age.

CM Hill, D Dimitriou, A Baya, R Webster… - …, 2014 - psycnet.apa.org
Objectives: To assess cognition in populations born and living at high altitude (HA; 3,700 m)
and low altitude (LA; 500 m) in Bolivia, who were similar for both socioeconomic status and …

Oxiracetam or fastigial nucleus stimulation reduces cognitive injury at high altitude

SL Hu, JT Shi, W Xiong, WN Li, LC Fang… - Brain and …, 2017 - Wiley Online Library
Background Cognitive impairment is common in people travelling to high altitude.
Oxiracetam and electrical stimulation of cerebellar fastigial nucleus may have beneficial …

Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission

JM Holley, S Stanbouly, MJ Pecaut, JS Willey, M Delp… - npj …, 2022 - nature.com
It has been proposed that neuroinflammatory response plays an important role in the
neurovascular remodeling in the brain after stress. The goal of the present study was to …

Cerebral blood flow at high altitude

PN Ainslie, AW Subudhi - High altitude medicine & biology, 2014 - liebertpub.com
Abstract Ainslie, Philip N., and Andrew W. Subudhi. Invited Review: Cerebral blood flow at
high altitude. High Alt Med Biol. 15: 133–140, 2014.—This brief review traces the last 50 …