Space microgravity alters neural stem cell division: Implications for brain cancer research on earth and in space

S Shaka, N Carpo, V Tran, C Cepeda… - International Journal of …, 2022 - mdpi.com
Considering the imminence of long-term space travel, it is necessary to investigate the
impact of space microgravity (SPC-µG) in order to determine if this environment has …

Impacts of spaceflight experience on human brain structure

HR McGregor, KE Hupfeld, O Pasternak, NE Beltran… - Scientific Reports, 2023 - nature.com
Spaceflight induces widespread changes in human brain morphology. It is unclear if these
brain changes differ with varying mission duration or spaceflight experience history (ie …

Characteristics of a rat model of an open craniocerebral injury at simulated high altitude

AY Yu, QH Xu, SL Hu, F Li, YJ Chen, Y Yin, G Zhu… - …, 2014 - journals.lww.com
To establish a rat model of an open craniocerebral injury at simulated high altitude and to
examine the characteristics of this model. Rats were divided randomly into a normobaric …

High-altitude cognitive impairment is prevented by enriched environment including exercise via VEGF signaling

C Koester-Hegmann, H Bengoetxea… - Frontiers in cellular …, 2019 - frontiersin.org
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive
impairment, mostly attributed to changes in brain perfusion and consequently neuronal …

Effects of a spaceflight analog environment on brain connectivity and behavior

K Cassady, V Koppelmans, P Reuter-Lorenz… - Neuroimage, 2016 - Elsevier
Sensorimotor functioning is adaptively altered following long-duration spaceflight. The
question of whether microgravity affects other central nervous system functions such as …

MRI evidence: acute mountain sickness is not associated with cerebral edema formation during simulated high altitude

K Mairer, M Göbel, M Defrancesco, M Wille, H Messner… - PloS one, 2012 - journals.plos.org
Acute mountain sickness (AMS) is a common condition among non-acclimatized individuals
ascending to high altitude. However, the underlying mechanisms causing the symptoms of …

Cognitive performance in high-altitude Andean residents compared with low-altitude populations: from childhood to older age.

CM Hill, D Dimitriou, A Baya, R Webster… - …, 2014 - psycnet.apa.org
Objectives: To assess cognition in populations born and living at high altitude (HA; 3,700 m)
and low altitude (LA; 500 m) in Bolivia, who were similar for both socioeconomic status and …

Effects of a fast cable car ascent to an altitude of 2700 meters on EEG and ECG

C Guger, W Domej, G Lindner, K Pfurtscheller… - Neuroscience …, 2005 - Elsevier
In the Eastern Alps, the Dachstein massif with a height of almost 3000m is an ideal location
for investigating the effects of changes in altitude on the human body. Within a few minutes …

Effect of chronic hypobaric hypoxia on components of the human event related potential

SB Singh, L Thakur, JP Anand… - Indian Journal of …, 2004 - search.proquest.com
BACKGROUND & OBJECTIVES: Induction to high altitude (HA) leads to deterioration in
cognitive functions. The event related potentials (ERPs) like P300 are reported to be affected …

Changes in C57BL6 mouse hippocampal transcriptome induced by hypergravity mimic acute corticosterone-induced stress

A Pulga, Y Porte, JL Morel - Frontiers in Molecular Neuroscience, 2016 - frontiersin.org
Centrifugation is a widely used procedure to study the impact of altered gravity on Earth, as
observed during spaceflights, allowing us to understand how a long-term physical constraint …