Preservation of neurovascular coupling to cognitive activity in anterior cerebrovasculature during incremental ascent to high altitude
WK Lefferts, JP DeBlois, JE Soriano… - … altitude medicine & …, 2020 - liebertpub.com
Background: High altitude sojourn challenges blood flow regulation in the brain, which may
contribute to cognitive dysfunction. Neurovascular coupling (NVC) describes the ability to …
contribute to cognitive dysfunction. Neurovascular coupling (NVC) describes the ability to …
Effects of simulated high altitude on event-related potential (P300) and auditory brain-stem responses
R Hayashi, Y Matsuzawa, K Kubo, T Kobayashi - Clinical Neurophysiology, 2005 - Elsevier
OBJECTIVE: This study investigated the effect of hyobaric hypoxia on cognitive function.
METHODS: We recorded the auditory brain-stem response (ABR) and auditory-evoked …
METHODS: We recorded the auditory brain-stem response (ABR) and auditory-evoked …
[HTML][HTML] Impacts of spaceflight experience on human brain structure
HR McGregor, KE Hupfeld, O Pasternak, NE Beltran… - Scientific Reports, 2023 - nature.com
Spaceflight induces widespread changes in human brain morphology. It is unclear if these
brain changes differ with varying mission duration or spaceflight experience history (ie …
brain changes differ with varying mission duration or spaceflight experience history (ie …
[HTML][HTML] Monitoring the impact of spaceflight on the human brain
MF Dinatolo, LY Cohen - Life, 2022 - mdpi.com
Extended exposure to radiation, microgravity, and isolation during space exploration has
significant physiological, structural, and psychosocial effects on astronauts, and particularly …
significant physiological, structural, and psychosocial effects on astronauts, and particularly …
Lifelong exposure to high‐altitude hypoxia in humans is associated with improved redox homeostasis and structural–functional adaptations of the neurovascular unit
BS Stacey, RL Hoiland, HG Caldwell… - The Journal of …, 2023 - Wiley Online Library
High‐altitude (HA) hypoxia may alter the structural–functional integrity of the neurovascular
unit (NVU). Herein, we compared male lowlanders (n= 9) at sea level (SL) and after 14 days …
unit (NVU). Herein, we compared male lowlanders (n= 9) at sea level (SL) and after 14 days …
Effects of a spaceflight analog environment on brain connectivity and behavior
Sensorimotor functioning is adaptively altered following long-duration spaceflight. The
question of whether microgravity affects other central nervous system functions such as …
question of whether microgravity affects other central nervous system functions such as …
[HTML][HTML] High-altitude cognitive impairment is prevented by enriched environment including exercise via VEGF signaling
C Koester-Hegmann, H Bengoetxea… - Frontiers in cellular …, 2019 - frontiersin.org
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive
impairment, mostly attributed to changes in brain perfusion and consequently neuronal …
impairment, mostly attributed to changes in brain perfusion and consequently neuronal …
Compromised white matter microstructural integrity after mountain climbing: evidence from diffusion tensor imaging
Abstract Zhang, Haiyan, Jianzhong Lin, Yingchun Sun, Yongxia Huang, Huiming Ye,
Xiaochuan Wang, Tianhe Yang, Xingtang Jiang, Jiaxing Zhang. Compromised white matter …
Xiaochuan Wang, Tianhe Yang, Xingtang Jiang, Jiaxing Zhang. Compromised white matter …
[HTML][HTML] Characteristics of a rat model of an open craniocerebral injury at simulated high altitude
AY Yu, QH Xu, SL Hu, F Li, YJ Chen, Y Yin, G Zhu… - …, 2014 - journals.lww.com
To establish a rat model of an open craniocerebral injury at simulated high altitude and to
examine the characteristics of this model. Rats were divided randomly into a normobaric …
examine the characteristics of this model. Rats were divided randomly into a normobaric …
[HTML][HTML] MRI evidence: acute mountain sickness is not associated with cerebral edema formation during simulated high altitude
K Mairer, M Göbel, M Defrancesco, M Wille, H Messner… - PloS one, 2012 - journals.plos.org
Acute mountain sickness (AMS) is a common condition among non-acclimatized individuals
ascending to high altitude. However, the underlying mechanisms causing the symptoms of …
ascending to high altitude. However, the underlying mechanisms causing the symptoms of …