Modern genomic sequencing technologies produce a large amount of data with reduced
cost per base; however, this data consists of short reads. This reduction in the size of the …

Genome assembly has always been complicated due to the inherent difficulties of
sequencing technologies, as well the computational methods used to process sequences …

The latest revolution in the DNA sequencing field has been brought about by the
development of automated sequencers that are capable of generating giga base pair data …

Background De novo genome assembly using NGS data remains a computation-intensive
task especially for large genomes. In practice, efficiency is often a primary concern and …

Bacterial genomes are simpler than mammalian ones, and yet assembling the former from
the data currently generated by high-throughput short-read sequencing machines still …

Background With the rapid development of the next generation sequencing (NGS)
technology, large quantities of genome sequencing data have been generated. Because of …

Background: The analysis of next-generation sequencing data from large genomes is a
timely research topic. Sequencers are producing billions of short sequence fragments from …

Genome sequencing has become routine, however genome assembly still remains a
challenge despite the computational advances in the last decade. In particular, the …

One of the most complex and computationally intensive tasks of genome sequence analysis
is genome assembly. Even today, few centres have the resources, in both software and …

Motivation: Assemblies of next-generation sequencing (NGS) data, although accurate, still
contain a substantial number of errors that need to be corrected after the assembly process …