A CHIMERIC ANTIGEN CONSISTING OF TYPE III SECRETION PROTEINS AS A CHLAMYDIA VACCINE CANDIDATE
S Liang - 2019 - macsphere.mcmaster.ca
Chlamydia is the most prevalent sexually transmitted bacterial infection in many developed
countries, including Canada. Untreated infections in women can lead to a number of …
countries, including Canada. Untreated infections in women can lead to a number of …
[PDF][PDF] Intranasal vaccination with a Chimeric Chlamydial Antigen BD584 confers protection against Chlamydia trachomatis genital tract infection
S Liang, JB Mahony - J Vaccines Immunol, 2020 - pdfs.semanticscholar.org
Chlamydia is the most common sexually transmitted infection of bacterial origin, and a
broadly protective vaccine is urgently needed given the largely asymptomatic nature of the …
broadly protective vaccine is urgently needed given the largely asymptomatic nature of the …
Immunization with chlamydial type III secretion antigens reduces vaginal shedding and prevents fallopian tube pathology following live C. muridarum challenge
DC Bulir, S Liang, A Lee, S Chong, E Simms, C Stone… - Vaccine, 2016 - Elsevier
Chlamydia trachomatis infections in women are often asymptomatic and if left untreated can
lead to significant late sequelae including pelvic inflammatory disease and tubal factor …
lead to significant late sequelae including pelvic inflammatory disease and tubal factor …
Chlamydial Type III Secretion System Needle Protein Induces Protective Immunity against Chlamydia muridarum Intravaginal Infection
EA Koroleva, NV Kobets… - BioMed research …, 2017 - Wiley Online Library
Chlamydia trachomatis imposes serious health problems and causes infertility. Because of
asymptomatic onset, it often escapes antibiotic treatment. Therefore, vaccines offer a better …
asymptomatic onset, it often escapes antibiotic treatment. Therefore, vaccines offer a better …
Identification and characterization of novel recombinant vaccine antigens for immunization against genital Chlamydia trachomatis
RN Coler, A Bhatia, JF Maisonneuve… - FEMS Immunology & …, 2009 - academic.oup.com
Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection
worldwide, with over 91 million cases estimated annually. An effective subunit vaccine …
worldwide, with over 91 million cases estimated annually. An effective subunit vaccine …
Protective immunity against mouse upper genital tract pathology correlates with high IFNγ but low IL-17 T cell and anti-secretion protein antibody responses induced …
C Lu, H Zeng, Z Li, L Lei, IT Yeh, Y Wu, G Zhong - Vaccine, 2012 - Elsevier
To search for optimal immunization conditions for inducing protective immunity against
upper genital tract pathologies caused by chlamydial intravaginal infection, we compared …
upper genital tract pathologies caused by chlamydial intravaginal infection, we compared …
Preclinical screen for protection efficacy of chlamydial antigens that are immunogenic in humans
C Lu, J Wang, G Zhong - Infection and immunity, 2023 - Am Soc Microbiol
To search for subunit vaccine candidates, immunogenic chlamydial antigens identified in
humans were evaluated for protection against both infection and pathology in a mouse …
humans were evaluated for protection against both infection and pathology in a mouse …
Protection against genital tract Chlamydia trachomatis infection following intranasal immunization with a novel recombinant MOMP VS2/4 antigen
The asymptomatic nature of most Chlamydia trachomatis infections and the lack of
appropriate effects by current prevention and management call for vaccine development. We …
appropriate effects by current prevention and management call for vaccine development. We …
Intranasal Vaccination with a Secreted Chlamydial Protein Enhances Resolution of Genital Chlamydia muridarum Infection, Protects against Oviduct Pathology, and …
There is currently no licensed vaccine against Chlamydia trachomatis, the leading cause of
sexually transmitted bacterial disease worldwide. Conventional vaccination attempts using …
sexually transmitted bacterial disease worldwide. Conventional vaccination attempts using …
[HTML][HTML] Immunogenicity and Protective Capacity of a Virus-like Particle Vaccine against Chlamydia trachomatis Type 3 Secretion System Tip Protein, CT584
E Webster, KW Seiger, SB Core, AL Collar… - Vaccines, 2022 - mdpi.com
An effective vaccine against Chlamydia trachomatis is urgently needed as infection rates
continue to rise and C. trachomatis causes reproductive morbidity. An obligate intracellular …
continue to rise and C. trachomatis causes reproductive morbidity. An obligate intracellular …