Objective: In animal studies, naloxone, an opioid receptor antagonist, improves tolerance to
hemorrhagic shock. The purpose of this study was to determine whether naloxone would …

This study was designed to evaluate effects of fentanyl (F) on heart rate (HR), systemic blood
pressure (SBP) and renal sympathetic nerve activity (RNA) in urethane-or halothane …

Sympathetic transduction of blood pressure (BP) is correlated negatively with resting muscle
sympathetic nerve activity (MSNA) in cross-sectional data, but the acute effects of increasing …

Excessive sympathetic outflow following trauma can lead to cardiac dysfunction,
inflammation, coagulopathy, and poor outcomes. We previously reported that buprenorphine …

Background: Many studies have been conducted to assess the effects of fentanyl on the
autonomic nervous system (ANS) by heart rate variability (HRV) analysis, but disagreement …

We tested the hypothesis that women have blunted sympathetic neural responses to
orthostatic stress compared with men, which may be elicited under hypovolemic conditions …

Background Hemorrhagic shock produces an immediate activation of the autonomic
nervous system and endogenous opioid pathways. Our studies have demonstrated that …

Sympathetic nerve activity influences cerebral blood flow, but it is unknown whether
augmented sympathetic nerve activity resets cerebral vasoreactivity to hypercapnia. This …

Adenosine increases heart rate and sympathetic nerve activity reflexively in conscious
humans through several mechanisms. The purpose of this study was to assess the relative …

In this study, we defined the nature of the interactions between sevoflurane and fentanyl on
spontaneous and reflex-evoked sympathetic activity, resting heart rate (HR), and mean …