Gingival epithelial barrier: regulation by beneficial and harmful microbes

N Takahashi, B Sulijaya, M Yamada-Hara… - Tissue …, 2019 - Taylor & Francis
The gingival epithelium acts as a physical barrier to separate the biofilm from the gingival
tissue, providing the first line of defense against bacterial invasion in periodontal disease …

Microbial and host factors that affect bacterial invasion of the gingiva

S Ji, Y Choi - Journal of Dental Research, 2020 - journals.sagepub.com
Periodontitis is a chronic inflammation of the periodontium caused by the loss of
homeostasis between subgingival biofilms and susceptible hosts. Bacterial invasion into the …

Epithelial barrier and oral bacterial infection

SE Groeger, J Meyle - Periodontology 2000, 2015 - Wiley Online Library
The oral epithelial barrier separates the host from the environment and provides the first line
of defense against pathogens, exogenous substances and mechanical stress. It consists of …

Importance of virulence factors for the persistence of oral bacteria in the inflamed gingival crevice and in the pathogenesis of periodontal disease

G Dahlen, A Basic, J Bylund - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is a chronic inflammation that develops due to a destructive tissue response to
prolonged inflammation and a disturbed homeostasis (dysbiosis) in the interplay between …

Host‐bacteria crosstalk at the dentogingival junction

MT Pöllänen, MA Laine, R Ihalin… - International journal of …, 2012 - Wiley Online Library
The dentogingival junction is of crucial importance in periodontal host defense both
structurally and functionally. Oral bacteria exert a constant challenge to the host cells and …

Key elements of gingival epithelial homeostasis upon bacterial interaction

JS Lee, Ö Yilmaz - Journal of Dental Research, 2021 - journals.sagepub.com
Epithelia are structurally integral elements in the fabric of oral mucosa with significant
functional roles. Similarly, the gingival epithelium performs uniquely critical tasks in …

Bacterial invasion and persistence: critical events in the pathogenesis of periodontitis?

S Ji, YS Choi, Y Choi - Journal of periodontal research, 2015 - Wiley Online Library
Periodontitis is chronic inflammation of the periodontium caused by the host's inflammatory
response to plaque biofilm, which destroys tooth‐supporting soft and hard tissues …

Innate cellular responses to the periodontal biofilm

M Benakanakere, DF Kinane - Periodontal Disease, 2012 - karger.com
This chapter addresses the host responses to the microbial biofilm that constitutes the
subgingival dental plaque. The host response to infection draws upon the innate …

The nexus between periodontal inflammation and dysbiosis

TE Van Dyke, PM Bartold, EC Reynolds - Frontiers in immunology, 2020 - frontiersin.org
The nexus between periodontal inflammation and the polymicrobial biofilm in the gingival
sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in …

The expression of gingival epithelial junctions in response to subgingival biofilms

GN Belibasakis, JI Kast, T Thurnheer, CA Akdis… - Virulence, 2015 - Taylor & Francis
Periodontitis is an infectious inflammatory disease that destroys the tooth-supporting tissues.
It is caused by the formation of subgingival biofilms on the surface of the tooth. Characteristic …