Background The gut bacteria-derived metabolite trimethylamine-N-oxide (TMAO) has been
discussed in various cardiometabolic diseases. However, evidence characterizing the …

The human gut microbiome and its metabolite Trimethylamine N-oxide (TMAO) are sensitive
to the human diet and are involved in the complex pathomechanisms that underpin …

Introduction The importance of gut microbiome in cardiovascular disease has been
increasingly recognized. Trimethylamine N-oxide (TMAO) is a gut microbe-derived …

Accumulating evidence has demonstrated that gut microbial-derived metabolite
trimethylamine N-oxide (TMAO) plays a crucial role in the pathogenesis of many diseases …

Background We had previously reported an increase in trimethylamine N-oxide (TMAO)
levels in patients with both compensated and decompensated heart failure (HF) and …

Background: The gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) has
recently been recognized as one of the novel marker for adverse cardiovascular events and …

Microbial trimethylamine (TMA)-lyase activity promotes the development of atherosclerosis
by generating of TMA, the precursor of TMA N-oxide (TMAO). TMAO is well documented, but …

Host-microbes interaction plays a crucial role in cardiovascular disease (CVD)
pathogenesis, mechanistically via metaorganismal pathways. The trimethylamine N-oxide …

Chronic kidney disease (CKD) patients have an increased risk of cardiovascular diseases
(CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine …

ABSTRACT Background Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–
related metabolite, is associated with cardiovascular disease (CVD). However, major dietary …