[HTML][HTML] Luteolin: a promising natural agent in management of pain in chronic conditions

F Ntalouka, A Tsirivakou - Frontiers in Pain Research, 2023 - frontiersin.org
Pain due to chronic conditions is a frequent and insufficiently addressed problem. Current
drug options for pain management (either in cases of chronic inflammatory conditions or …

Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

N Aziz, MY Kim, JY Cho - Journal of ethnopharmacology, 2018 - Elsevier
Abstract Ethnopharmacological relevance Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) has
been identified as commonly present in plants. Plants with a high luteolin content have been …

From nature to therapy: Luteolin's potential as an immune system modulator in inflammatory disorders

MS Hussain, G Gupta, A Goyal, R Thapa… - … of biochemical and …, 2023 - Wiley Online Library
Inflammation is an essential immune response that helps fight infections and heal tissues.
However, chronic inflammation has been linked to several diseases, including cancer …

Effects of intrathecal and intracerebroventricular administration of luteolin in a rat neuropathic pain model

K Hara, Y Haranishi, T Terada, Y Takahashi… - Pharmacology …, 2014 - Elsevier
Luteolin, a major component of flavones, is known to have various physiological properties.
Although luteolin reportedly has an antinociceptive effect on acute and inflammatory pain …

[HTML][HTML] Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on In Vivo Pharmacological Effects and Bioavailability Traits

Y Taheri, J Sharifi-Rad, G Antika, YB Yılmaz… - … Medicine and Cellular …, 2021 - hindawi.com
Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As
many other natural flavonoids, it is often found in combination with glycosides in many fruits …

Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice

M Hashemzaei, M Abdollahzadeh… - … of Complementary and …, 2017 - degruyter.com
Background Neuropathic pain (NP) is a common condition accompanied by nerve injury. To
date, there is no definite treatment approved for this disorder. In addition, many drugs that …

Lutein, a versatile phyto-nutraceutical: An insight on pharmacology, therapeutic indications, challenges and recent advances in drug delivery

T Madaan, AN Choudhary, S Gyenwalee, S Thomas… - PharmaNutrition, 2017 - Elsevier
Carotenoids are natural pigments known for their ability to provide protection from ultraviolet
radiation and singlet-oxygen-induced damage such as mutation, immunosuppression, and …

Evaluation of anti-nociceptive and anti-inflammatory effect of luteolin in mice

X Fan, K Du, N Li, Z Zheng, Y Qin, J Liu… - Journal of …, 2018 - dl.begellhouse.com
Flavonoids are polyphenolic compounds that not only impart coloration to plants and fruits,
but also protect plants from pathogens, radiation, etc. They serve as a nutrient to plants and …

Luteolin transforms the polarity of bone marrow-derived macrophages to regulate the cytokine storm

S Wang, S Xu, J Zhou, L Zhang, X Mao, X Yao… - Journal of …, 2021 - Springer
Background Macrophages are indispensable regulators of inflammatory responses.
Macrophage polarisation and their secreted inflammatory factors have an association with …

Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin

G Seelinger, I Merfort, CM Schempp - Planta medica, 2008 - thieme-connect.com
Luteolin is a flavone which occurs in medicinal plants as well as in some vegetables and
spices. It is a natural anti-oxidant with less pro-oxidant potential than the flavonol quercetin …