Capsaicin for weight control:“Exercise in a pill”(or just another fad)?

A Szallasi - Pharmaceuticals, 2022 - mdpi.com
Medical management of obesity represents a large unmet clinical need. Animal experiments
suggest a therapeutic potential for dietary capsaicin, the pungent ingredient in hot chili …

Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications

J Zheng, S Zheng, Q Feng, Q Zhang… - Bioscience reports, 2017 - portlandpress.com
Obesity is a growing public health problem, which has now been considered as a pandemic
non-communicable disease. However, the efficacy of several approaches for weight loss is …

Capsaicin and capsiate could be appropriate agents for treatment of obesity: A meta-analysis of human studies

C Zsiborás, R Mátics, P Hegyi, M Balaskó… - Critical Reviews in …, 2018 - Taylor & Francis
Consumption of capsaicin or its nonpungent analogues, capsinoids has been reported to
affect energy expenditure and fat oxidation, although available data are still controversial …

Advances in antiobesity mechanisms of capsaicin

Y Wang, Y Zhou, J Fu - Current Opinion in Pharmacology, 2021 - Elsevier
Obesity is a global epidemic that affects the lives and health of millions of people. The
prevention and treatment of obesity have become a significant public health challenge …

Capsaicinoids: a spicy solution to the management of obesity?

A Tremblay, H Arguin, S Panahi - International journal of obesity, 2016 - nature.com
Capsaicin is the molecule that is responsible for the pungency of hot peppers. It stimulates
the sympathoadrenal system that mediates the thermogenic and anorexigenic effects of …

The effects of capsaicin intake on weight loss among overweight and obese subjects: a systematic review and meta-analysis of randomised controlled trials

W Zhang, Q Zhang, L Wang, Q Zhou, P Wang… - British Journal of …, 2023 - cambridge.org
Animal studies have shown that capsaicin plays a positive role in weight management.
However, the results in human research are controversial. Therefore, the present systematic …

Anti-obesity effects of capsaicin and the underlying mechanisms: A review

R Li, Y Lan, C Chen, Y Cao, Q Huang, CT Ho, M Lu - Food & function, 2020 - pubs.rsc.org
Obesity and overweight have become serious health problems in the world and are linked to
a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely …

Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?

JL Silva, EA Santos, JI Alvarez-Leite - Nutrients, 2023 - mdpi.com
Capsaicin, a lipophilic, volatile compound, is responsible for the pungent properties of chili
peppers. In recent years, a significant increase in investigations into its properties has …

Capsaicin as an anti-obesity drug

FW Leung - Capsaicin as a therapeutic molecule, 2014 - Springer
Laboratory studies support a role of capsaicin as an anti-obesity agent. Intestinal mucosal
afferent nerves appear to play a role in controlling adipose tissue distribution between …

The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans

MJ Ludy, GE Moore, RD Mattes - Chemical senses, 2012 - academic.oup.com
Consumption of spicy foods containing capsaicin, the major pungent principle in hot
peppers, reportedly promotes negative energy balance. However, many individuals abstain …