[PDF][PDF] Streamlined Unknown Screening for Postmortem Analysis

P Negri, OG Cabrices, D Fritch, M Stauffer, N Koenig… - AB Sciex, 2019 - lcms.cz
Gathering evidence to determine the cause of death is paramount in the service of the public
interest and the judicial process. To this end, accurate identification of drugs present in …

Postmortem drug screening by non-targeted and targeted ultra-performance liquid chromatography-mass spectrometry technology

TG Rosano, M Wood, TA Swift - Journal of analytical toxicology, 2011 - academic.oup.com
In the medical examiner setting, comprehensive drug screening is an essential analytical
tool in the investigation of cause and manner of death. We have validated non-targeted and …

Overnight toxicology–fast targeted screening of drugs and poisons in post-mortem blood

D Gerostamoulos, J Beyer, JL Woods, N George… - Pathology, 2010 - Elsevier
Introduction Targeted screening methods that cover a broad range of common drugs and
drugs of abuse are essential for forensic laboratories. The most common techniques used …

Comparing ELISA and LC–MS-MS: A Simple, Targeted Postmortem Blood Screen

DM Swanson, JM Pearson… - Journal of Analytical …, 2022 - academic.oup.com
A comprehensive screening method that is specific, accurate and customizable is necessary
in any forensic toxicology laboratory. Most laboratories utilize some form of immunoassay …

Screening of novel psychoactive substances in postmortem matrices by liquid chromatography–tandem mass spectrometry (LC–MS-MS)

M Fagiola, T Hahn, J Avella - Journal of Analytical Toxicology, 2018 - academic.oup.com
Novel psychoactive substances (NPS) are newly emerging compounds, natural and
synthetic, that are often sold as “legal” alternatives to controlled substances. These …

Assessment of urine drug screen utility at autopsy to predict laboratory postmortem blood toxicology

C Arndt, MA Huestis, HC Jarvis… - Journal of Forensic …, 2024 - Wiley Online Library
When faced with increasing drug‐related deaths and decline in practicing forensic
pathologists, the need to quickly identify toxicology‐related deaths is evident in order to …

Simultaneous quantitative analysis of 39 common toxicological drugs for increased efficiency in an ante-and postmortem laboratory

DC Mata, JF Davis - Forensic Science International, 2022 - Elsevier
Background A novel forensic method was developed to quantitate 39 drugs of toxicological
interest for ante-mortem and postmortem analysis. This method was created to combine and …

Method consolidation to improve scope and efficiency in postmortem toxicology

J Gevorkyan, M Wong, S Pearring… - Journal of Analytical …, 2020 - academic.oup.com
Systematic toxicological approaches that employ both ideology changes and improvements
in instrumentation and sample extraction allow for improved toxicology testing efficiency …

Simultaneous Screening and Quantitation of Drugs and Their Metabolites in Postmortem Samples by Liquid Chromatography–High-Resolution Mass Spectrometry …

E Rab, S Martin, A Freemont, S Maslin… - Journal of Analytical …, 2023 - academic.oup.com
Screening of postmortem blood and urine samples is used to identify compounds that may
have contributed to an individual's death. Toxicologically significant compounds detected by …

Drug Screening in Medical Examiner Casework by High-Resolution Mass Spectrometry (UPLC–MSE-TOF)

TG Rosano, M Wood, K Ihenetu… - Journal of analytical …, 2013 - academic.oup.com
Postmortem drug findings yield important analytical evidence in medical examiner
casework, and chromatography coupled with nominal mass spectrometry (MS) serves as the …