Glioblastoma multiforme, the deadliest primary brain tumor, is characterized by an excessive
and aberrant neovascularization. The initial expectations raised by anti-angiogenic drugs …

Glioblastoma, a subset of aggressive brain tumors, deploy several means to increase blood
vessel supply dedicated to the tumor mass. This includes typical program borrowed from …

Abstract Purpose of Review To summarize the mechanisms of tumor angiogenesis and
resistance to antiangiogenic therapy, and the influence on tumor microenvironment. Recent …

Glioblastoma is among the most common tumor of the central nervous system in adults.
Overall survival has not significantly improved over the last decade, even with optimizing …

Introduction: Glioblastoma is invariably deadly and is characterized by extensive
vascularization and macrophage-dominant immunosuppression; nevertheless, anti …

Treatment of adult brain tumors, in particular glioblastoma, remains a significant clinical
challenge, despite modest advances in surgical technique, radiation, and …

Blood vessel formation is a fundamental process that occurs during both normal and
pathologic periods of tissue growth. In aggressive malignancies such as glioblastoma …

Despite aggressive surgery, radiotherapy and chemotherapy, malignant gliomas remain
uniformly fatal. To progress, these tumours stimulate the formation of new blood vessels …

Glioblastoma (GB) is highly vascularised tumour, known to exhibit enhanced infiltrative
potential. One of the characteristics of glioblastoma is microvascular proliferation …

Biochemical and biophysical cues governing glioblastoma (GBM) progression are complex
and dynamic. Tumor blood vessels, often recognized only by their transport functions, are …