Research Progress on Quantification Methods of Drug Concentration of Monoclonal Antibodies
J Zhang, L Hu, H Shao - Current Pharmaceutical Analysis, 2022 - ingentaconnect.com
Background: With the development of monoclonal antibodies (mAbs) from the first
generation of mice to the fourth generation of human origin, the efficacy and safety in the …
generation of mice to the fourth generation of human origin, the efficacy and safety in the …
Research progress of monoclonal antibodies in pharmacokinetic characteristics, analysis methods and method validation
X ZHU, Z LI, X TIAN, X ZHANG - Chinese Journal of …, 2021 - manu41.magtech.com.cn
In recent years, monoclonal antibodies (mAbs) have been developing rapidly and widely
used in fields of tumor, immunity, blood and other systemic diseases. Global share of mAbs …
used in fields of tumor, immunity, blood and other systemic diseases. Global share of mAbs …
Immunoassays for measuring serum concentrations of monoclonal antibodies and anti-biopharmaceutical antibodies in patients
Monoclonal antibodies (mAbs) may be used as biopharmaceuticals to treat various
diseases, ranging from oncology to inflammatory and cardiovascular affections. Trustworthy …
diseases, ranging from oncology to inflammatory and cardiovascular affections. Trustworthy …
Bioanalytical methods for the quantification of therapeutic monoclonal antibodies and their application in clinical pharmacokinetic studies
CWN Damen, JHM Schellens, JH Beijnen - Human antibodies, 2009 - content.iospress.com
Monoclonal antibodies (mAbs) are an upcoming group of therapeutic compounds used to
treat various types of diseases. Currently more than 100 mAbs are in clinical development …
treat various types of diseases. Currently more than 100 mAbs are in clinical development …
Therapeutic monoclonal antibody concentration monitoring: free or total?
Most therapeutic monoclonal antibodies are designed to bind a specific antigen to elicit
pharmacological effects. Accurate quantification of a therapeutic monoclonal antibody in …
pharmacological effects. Accurate quantification of a therapeutic monoclonal antibody in …
[HTML][HTML] Antibody drug quantitation in coexistence with anti-drug antibodies on nSMOL bioanalysis
N Iwamoto, A Hamada, T Shimada - Analytical biochemistry, 2018 - Elsevier
Therapeutic monoclonal antibodies (mAbs) are developed for treatment of diverse cancers
and autoimmune diseases. For expansion of mAbs approval against unapproved diseases …
and autoimmune diseases. For expansion of mAbs approval against unapproved diseases …
An Introduction to Bioanalysis of Monoclonal Antibodies
V Ramani, S Bhardwaj, OA Ismaiel - An Introduction to Bioanalysis of …, 2022 - Springer
Therapeutic monoclonal antibodies are one of the largest and fastest growing class of large-
molecule biotherapeutics. Accurate and reliable quantification of these biotherapeutics in …
molecule biotherapeutics. Accurate and reliable quantification of these biotherapeutics in …
Quality assessment of bioanalytical quantification of monoclonal antibody drugs
JW Lee, M Kelley - Therapeutic delivery, 2011 - Future Science
Monoclonal antibody biotherapeutics are developed to bind to a specific target to affect the
target's biological effect. Reliable measurements of monoclonal antibodies in biological …
target's biological effect. Reliable measurements of monoclonal antibodies in biological …
Advances in therapeutic drug monitoring of monoclonal antibody drugs
RF ZHU - Chinese Pharmaceutical Journal, 2018 - pesquisa.bvsalud.org
Monoclonal antibody (mAb) drugs currently are an important field in drug development and
playing a wide role in the treatment of autoimmune diseases and tumor. However …
playing a wide role in the treatment of autoimmune diseases and tumor. However …
A surey of bioanalysis methods for antibody drugs
F ZHENG, Z JIA, X XIE, M HAN… - Chinese Journal of …, 2020 - manu41.magtech.com.cn
Antibody drugs have become the first choice for clinical treatment of many diseases due to
their advantages of targeting, high specificity and low toxicity. However, the disposal …
their advantages of targeting, high specificity and low toxicity. However, the disposal …