Donor management and lung preservation for lung transplantation

L Munshi, S Keshavjee, M Cypel - The Lancet Respiratory Medicine, 2013 - thelancet.com
Although lung transplantation has become a life-saving option for patients with end-stage
lung disease, this intervention is hampered by a shortage of lungs in view of the growing …

Novel approaches to expanding the lung donor pool: donation after cardiac death and ex vivo conditioning

M Cypel, JC Yeung… - Clinics in chest medicine, 2011 - chestmed.theclinics.com
Lung transplantation (LTx) represents a unique lifesaving therapy for patients suffering from
endstage lung disease. Ever since the world's first successful lung transplant was performed …

[HTML][HTML] Ex vivo lung perfusion–state of the art in lung donor pool expansion

AF Popov, A Sabashnikov, NP Patil… - … science monitor basic …, 2015 - ncbi.nlm.nih.gov
Lung transplantation remains the gold standard for patients with end-stage lung disease.
Nevertheless, the number of suitable donor lungs for the increasing number of patients on …

Donor selection and management

GI Snell, M Paraskeva… - Seminars in respiratory and …, 2013 - thieme-connect.com
This article reviews recent developments in the selection, assessment, and management of
the potential lung donor, which aim to increase donor organ use. The scarcity of suitable …

Advances in lung preservation

TN Machuca, M Cypel, S Keshavjee - Surgical Clinics, 2013 - surgical.theclinics.com
Lung transplantation is a well-established therapy for patients with end-stage lung disease.
The 2012 report from the International Society for Heart and Lung Transplantation Registry …

Portable normothermic ex-vivo lung perfusion, ventilation, and functional assessment with the Organ Care System on donor lung use for transplantation from extended …

G Loor, G Warnecke, MA Villavicencio… - The Lancet …, 2019 - thelancet.com
Background Donor lung use for transplantation is the lowest among solid organ tranplants
because of several complex and multifactorial reasons; one area that could have a …

Standard donor lung procurement with normothermic ex vivo lung perfusion: a prospective randomized clinical trial

A Slama, L Schillab, M Barta, A Benedek… - The Journal of Heart and …, 2017 - Elsevier
Background Ex vivo lung perfusion (EVLP) was primarily developed for evaluation of
impaired donor lungs. The good clinical results raise the question for its possible impact on …

Lung Transplantation from Donors after Circulatory Death Using Portable Ex Vivo Lung Perfusion

S Bozso, V Vasanthan, JGY Luc… - Canadian respiratory …, 2015 - Wiley Online Library
BACKGROUND: Donation after circulatory death is a novel method of increasing the number
of donor lungs available for transplantation. Using organs from donors after circulatory death …

Improving donor lung evaluation: a new approach to increase organ supply for lung transplantation

AJ Fisher, JH Dark, PA Corris - Thorax, 1998 - thorax.bmj.com
Major technical and pharmacological advances mean that lung transplantation now oVers a
realistic opportunity for long term survival in selected patients with end stage pulmonary …

Evaluation and management of the potential lung donor

A Courtwright, E Cantu - Clinics in chest medicine, 2017 - chestmed.theclinics.com
The number of lung transplants in the United States grew by 250% over the past 20 years,
from 932 in 1996 to 2327 in 2016. 1 This dramatic increase, which was mirrored worldwide …