Background This study aimed to investigate the value of microRNA (miR)‐21 for predicting
sepsis risk and its correlation with inflammation, disease severity as well as 28‐day mortality …

MicroRNAs (miRNAs) are a class of short noncoding RNAs that regulate the translation of
target messenger RNA (mRNA) and consequently participate in a variety of biological …

Inflammatory stimuli are usually associated with homeostatic responses, which have an
important function in protecting the body from excessive inflammatory damage. Previous …

The molecular mechanisms of acute lung injury are incompletely understood. MicroRNAs
(miRNAs) are crucial biological regulators that act by suppressing their target genes and are …

Appropriate innate immune responses are required to protect an organism against foreign
pathogens, and the immune response must be tightly controlled. Here, we report a new …

Accumulating evidences have confirmed that miRNAs have important roles in sepsis.
Myeloid-derived suppressor cells (MDSCs) enhance late sepsis development through …

Objective: Serum levels of microRNA have been proposed as biomarkers in various
inflammatory diseases. However, up to now, their clinical relevance in critical illness and …

Background Sepsis is a systemic inflammatory response syndrome. MicroRNA (miRNA)
plays an important role in immune cell activation, inflammatory cytokine release and immune …

Background Immunosuppression has been recognized as a major cause of sepsis-related
mortality. Currently, there is much interest in identifying central hubs controlling septic …

Objectives: Septic shock is a life-threatening clinical situation associated with acute
myocardial and vascular dysfunction, whose pathophysiology is still poorly understood …