Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges

EF Lind, AR Elford, PS Ohashi - The Journal of Immunology, 2013 - journals.aai.org
Recent studies have begun to define the role of micro-RNAs in regulating the immune
response. Micro-RNA155 (mir-155) has been shown to play a role in germinal center …

MicroRNA-125b potentiates macrophage activation

AA Chaudhuri, AYL So, N Sinha… - The Journal of …, 2011 - journals.aai.org
Abstract MicroRNA (miR)-125b expression is modulated in macrophages in response to
stimulatory cues. In this study, we report a functional role of miR-125b in macrophages. We …

MicroRNA-155 regulates host immune response to postviral bacterial pneumonia via IL-23/IL-17 pathway

A Podsiad, TJ Standiford… - … of Physiology-Lung …, 2016 - journals.physiology.org
Postinfluenza bacterial pneumonia is associated with significant mortality and morbidity.
MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression …

[HTML][HTML] MicroRNA-203 acts as a potent suppressor in septic shock by alleviating lung injury via inhibition of VNN1

L Ling, HT Lu, HF Wang, MJ Shen… - Kidney and Blood …, 2019 - karger.com
Background: Septic shock, the most serious complication of sepsis, is a life-threatening
disease that is mainly characterized by hypoperfusion and multiple organ failure. Various …

[HTML][HTML] Turning 21: induction of miR-21 as a key switch in the inflammatory response

FJ Sheedy - Frontiers in immunology, 2015 - frontiersin.org
miR-21 is one of the most highly expressed members of the small non-coding microRNA
family in many mammalian cell types. Its expression is further enhanced in many diseased …

Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis

L Tong, C Tang, C Cai, X Guan - Bioengineered, 2020 - Taylor & Francis
Regulatory mechanisms of microRNAs (miRNAs) in the development of intestinal sepsis are
unclear. This study investigated the role of rno-miR-146b-5p in sepsis-induced intestinal …

MicroRNA 21 elicits a pro-inflammatory response in macrophages, with exosomes functioning as delivery vehicles

R Madhyastha, H Madhyastha, QI Nurrahmah… - Inflammation, 2021 - Springer
MicroRNAs can regulate inflammatory responses by modulating macrophage polarization.
Although microRNA miR-21 is linked to crucial processes involved in inflammatory …

MiR-150-5p protects against septic acute kidney injury via repressing the MEKK3/JNK pathway

L Shi, Y Zhang, Y Xia, C Li, Z Song, J Zhu - Cellular signalling, 2021 - Elsevier
Background Septic acute kidney injury (AKI) is associated with increased morbidity and
mortality in critically ill patients. MicroRNA is reportedly involved in sepsis-induced organ …

Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review

WD Xu, SY Feng, AF Huang - Inflammation Research, 2022 - Springer
Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …

MicroRNA‑93 contributes to the suppression of lung inflammatory responses in LPS‑induced acute lung injury in mice via the TLR4/MyD88/NF‑κB signaling pathway

H Gao, D Xiao, L Gao, X Li - … Journal of Molecular …, 2020 - spandidos-publications.com
Acute lung injury (ALI) is a severe inflammatory lung disease with a rapid onset. The anti‑
inflammatory functions of microRNA‑93 (miRNA/miR‑93) have been described in various …