It is well established that the survival and transmission of parasitic helminths (worms) in their
mammalian hosts is dependent on down-regulation of the immune system; less well …

Worldwide, more than a billion people are infected with helminths. These worm infections
generally do not lead to mortality, however, they are chronic in nature and can lead to …

By definition, parasites harm their hosts. Yet substantial evidence from animal models of
human disease support the hypothesis that infection with helminths can suppress the …

There is unequivocal evidence that parasites influence the immune activity of their hosts,
and many of the classical examples of this are drawn from assessment of helminth infections …

Parasitic infections are a major theme in the “hygiene hypothesis”, as allergies and
autoimmune diseases are less prevalent in countries with higher burdens of helminths and …

Helminths are able to modulate and suppress the hosts' immune response in order to
promote their own survival. This ability to alter immune responses could be of potential …

Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

The field of infectious disease immunology is at an exciting intersection with new concepts in
immune regulation meeting with the dynamics of infectious diseases. We discuss how the …

Parasitic helminths have an inclination to be long-lived invaders with certain human
parasites reported as surviving for in excess of a decade. Such longevity tends to be …