Structure-function coupling and hierarchy-specific antidepressant response in major depressive disorder

X Wang, L Xue, L Hua, J Shao, R Yan, Z Yao… - Psychological …, 2024 - cambridge.org
BackgroundExtensive research has explored altered structural and functional networks in
major depressive disorder (MDD). However, studies examining the relationships between …

Functional gradient alteration in individuals with cognitive vulnerability to depression

J Wang, Y Zhou, J Ding, J Xiao - Journal of Psychiatric Research, 2021 - Elsevier
Background Establishing a better understanding of the structure of the hierarchy is a primary
goal of neuroscience. Recent research has highlighted a connectome gradient dysfunction …

[HTML][HTML] A distinctive subcortical functional connectivity pattern linking negative affect and treatment outcome in major depressive disorder

YK Wu, YA Su, LL Zhu, CG Yan, JT Li, JY Lin… - Translational …, 2024 - nature.com
Major depressive disorder (MDD) is associated with functional disturbances in subcortical
regions. In this naturalistic prospective study (NCT03294525), we aimed to investigate …

Distinct MRI-based functional and structural connectivity for antidepressant response prediction in major depressive disorder

X Wang, L Xue, J Shao, Z Dai, L Hua, R Yan… - Clinical …, 2024 - Elsevier
Objective Emerging studies have identified treatment-related connectome predictors in
major depressive disorder (MDD). However, quantifying treatment-responsive patterns in …

Mapping neurophysiological subtypes of major depressive disorder using normative models of the functional connectome

X Sun, J Sun, X Lu, Q Dong, L Zhang, W Wang, J Liu… - Biological …, 2023 - Elsevier
Background Major depressive disorder (MDD) is a highly heterogeneous disorder that
typically emerges in adolescence and can occur throughout adulthood. Studies aimed at …

Individualized fMRI connectivity defines signatures of antidepressant and placebo responses in major depression

K Zhao, H Xie, GA Fonzo, X Tong, N Carlisle… - Molecular …, 2023 - nature.com
Though sertraline is commonly prescribed in patients with major depressive disorder (MDD),
its superiority over placebo is only marginal. This is in part due to the neurobiological …

Severity of current depression and remission status are associated with structural connectome alterations in major depressive disorder

J Repple, M Mauritz, S Meinert, SC de Lange… - Molecular …, 2020 - nature.com
Major depressive disorder (MDD) is associated to affected brain wiring. Little is known
whether these changes are stable over time and hence might represent a biological …

[HTML][HTML] Intrinsic connectomes are a predictive biomarker of remission in major depressive disorder

MS Korgaonkar, AN Goldstein-Piekarski, A Fornito… - Molecular …, 2020 - nature.com
Although major depressive disorder (MDD) is associated with altered functional coupling
between disparate neural networks, the degree to which such measures are ameliorated by …

[HTML][HTML] Multimodal investigation of network level effects using intrinsic functional connectivity, anatomical covariance, and structure-to-function correlations in …

D Scheinost, SE Holmes, N DellaGioia… - …, 2018 - nature.com
Converging evidence suggests that major depressive disorder (MDD) affects multiple large-
scale brain networks. Analyses of the correlation or covariance of regional brain structure …

Structural alterations of the brain preceded functional alterations in major depressive disorder patients: evidence from multimodal connectivity

Z Yao, Y Zou, W Zheng, Z Zhang, Y Li, Y Yu… - Journal of affective …, 2019 - Elsevier
Background Recent studies showed that major depressive disorder (MDD) has been
involved in abnormal functional and structural connections in specific brain regions …